The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5559: Diacylglycerol kinase, alpha 80kDa

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Diacylglycerol kinase activity GO:0004143
Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate.
9 O88673 (/IDA) P23743 (/IDA) P49619 (/IDA) P49620 (/IDA) P49621 (/IDA) Q01583 (/IDA) Q5KSL6 (/IDA) Q6NS52 (/IDA) Q9Y6T7 (/IDA)
Diacylglycerol kinase activity GO:0004143
Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate.
9 A8JQ65 (/ISS) B3LXF2 (/ISS) B3NYS4 (/ISS) B4I4Y1 (/ISS) B4JHJ7 (/ISS) B4K6T8 (/ISS) B4PRE2 (/ISS) B4R0A5 (/ISS) Q6DIC8 (/ISS)
Diacylglycerol kinase activity GO:0004143
Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate.
7 A0JP53 (/ISO) E9Q7N4 (/ISO) F6UUZ3 (/ISO) O88673 (/ISO) Q6DIC8 (/ISO) Q6NS52 (/ISO) Q91WG7 (/ISO)
Diacylglycerol kinase activity GO:0004143
Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate.
4 P23743 (/TAS) P49619 (/TAS) Q5KSL6 (/TAS) Q9Y6T7 (/TAS)
Diacylglycerol kinase activity GO:0004143
Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate.
2 A8JQ65 (/NAS) Q01583 (/NAS)
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
1 O88673 (/IDA)
Kinase activity GO:0016301
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
1 P23743 (/IDA)
Kinase activity GO:0016301
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
1 O88673 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 A0JP53 (/ISO)

There are 29 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein kinase C-activating G-protein coupled receptor signaling pathway GO:0007205
The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).
8 A8JQ65 (/ISS) B3LXF2 (/ISS) B3NYS4 (/ISS) B4I4Y1 (/ISS) B4JHJ7 (/ISS) B4K6T8 (/ISS) B4PRE2 (/ISS) B4R0A5 (/ISS)
Protein oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
8 A8JQ65 (/ISS) B3LXF2 (/ISS) B3NYS4 (/ISS) B4I4Y1 (/ISS) B4JHJ7 (/ISS) B4K6T8 (/ISS) B4PRE2 (/ISS) B4R0A5 (/ISS)
Diacylglycerol metabolic process GO:0046339
The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.
5 A0JP53 (/ISO) E9Q7N4 (/ISO) F6UUZ3 (/ISO) O88673 (/ISO) Q6DIC8 (/ISO)
Platelet activation GO:0030168
A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
4 P23743 (/TAS) P49619 (/TAS) Q5KSL6 (/TAS) Q9Y6T7 (/TAS)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
3 E9Q7N4 (/ISO) F6UUZ3 (/ISO) Q6DIC8 (/ISO)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
3 E9Q7N4 (/ISO) F6UUZ3 (/ISO) Q6DIC8 (/ISO)
Glycerolipid metabolic process GO:0046486
The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis.
3 P23743 (/IDA) P49619 (/IDA) Q9Y6T7 (/IDA)
Glycerolipid metabolic process GO:0046486
The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis.
3 O88673 (/ISO) Q6NS52 (/ISO) Q91WG7 (/ISO)
Lipid phosphorylation GO:0046834
The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.
3 P23743 (/IDA) P49619 (/IDA) Q9Y6T7 (/IDA)
Lipid phosphorylation GO:0046834
The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.
3 O88673 (/ISO) Q6NS52 (/ISO) Q91WG7 (/ISO)
Phosphorylation GO:0016310
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
2 A8JQ65 (/NAS) Q01583 (/NAS)
Diacylglycerol metabolic process GO:0046339
The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.
2 P23743 (/IDA) Q5KSL6 (/IDA)
Phosphatidic acid biosynthetic process GO:0006654
The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
1 P23743 (/IDA)
Phosphatidic acid biosynthetic process GO:0006654
The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
1 O88673 (/ISO)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q5KSL6 (/IDA)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q6DIC8 (/ISS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 P49619 (/TAS)
Protein kinase C-activating G-protein coupled receptor signaling pathway GO:0007205
The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).
1 A0JP53 (/ISO)
Protein kinase C-activating G-protein coupled receptor signaling pathway GO:0007205
The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).
1 P49620 (/TAS)
Phosphorylation GO:0016310
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
1 Q01583 (/IDA)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
1 Q5KSL6 (/IDA)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
1 Q6DIC8 (/ISS)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
1 P23743 (/TAS)
Olfactory behavior GO:0042048
The behavior of an organism in response to an odor.
1 Q03603 (/IMP)
Thermotaxis GO:0043052
The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.
1 Q03603 (/IMP)
Diacylglycerol metabolic process GO:0046339
The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.
1 Q6DIC8 (/ISS)
Regulation of long-term neuronal synaptic plasticity GO:0048169
A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.
1 Q03603 (/IMP)
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
1 P49620 (/IEP)
Protein oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 A0JP53 (/ISO)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 A8JQ65 (/ISS) B3LXF2 (/ISS) B3NYS4 (/ISS) B4I4Y1 (/ISS) B4JHJ7 (/ISS) B4K6T8 (/ISS) B4PRE2 (/ISS) B4R0A5 (/ISS)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
8 A8JQ65 (/ISS) B3LXF2 (/ISS) B3NYS4 (/ISS) B4I4Y1 (/ISS) B4JHJ7 (/ISS) B4K6T8 (/ISS) B4PRE2 (/ISS) B4R0A5 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 P23743 (/TAS) P49619 (/TAS) P49621 (/TAS) Q5KSL6 (/TAS) Q9Y6T7 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 O88673 (/IDA) Q5KSL6 (/IDA) Q6NS52 (/IDA) Q9Y6T7 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 E9Q7N4 (/ISO) F6UUZ3 (/ISO) Q6DIC8 (/ISO) Q6NS52 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 O88673 (/IDA) Q9Y6T7 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 P23743 (/IDA) P49621 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 A0JP53 (/ISO)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
1 A0JP53 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q6NS52 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q6DIC8 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 O88673 (/ISO)