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CATH Superfamily 3.30.590.10

Glutamine synthetase/guanido kinase, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Glutamine synthetase/guanido kinase, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2952: Probable glutamine synthetase glnA3

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutamine synthetase. [EC: 6.3.1.2]
ATP + L-glutamate + NH(3) = ADP + phosphate + L-glutamine.
  • Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.
  • Several types have been described, differing in their oligomeric structures and cofactor requirements.
 14 A0A045JPL1 A0A0E8V495 A0A0G4E150 A0A0H3LGQ8 A0A0H3M4Y5 A0A109S7X3 A0A109SNT8 A0A197J470 A5U3P5 F8MA20
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