View in Gene3D

CATH Superfamily 3.30.559.10

Chloramphenicol acetyltransferase-like domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Chloramphenicol acetyltransferase-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 22296: Phenolic glucoside malonyltransferase 2

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Anthocyanin 5-O-glucoside 6'''-O-malonyltransferase. [EC: 2.3.1.172]
Malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D- glucoside = CoA + 4'''-demalonylsalvianin.
  • Specific for the penultimate step in salvianin biosynthesis.
  • The enzyme also catalyzes the malonylation of shisonin to malonylshisonin (cyanidin 3-O-(6''-O-p-coumaryl-beta-D-glucoside)-5- (6'''-O-malonyl-beta-D-glucoside)).
  • The compounds 4'''-demalonylsalvianin, salvianin, pelargonidin 3,5- diglucoside and delphinidin 3,5-diglucoside cannot act as substrates.
 1 Q8W1W9
Anthocyanin 5-(6'''-hydroxycinnamoyltransferase). [EC: 2.3.1.153]
4-hydroxycinnamoyl-CoA + anthocyanidin 3,5-diglucoside = CoA + anthocyanidin 3-glucoside 5-(6-O-4-hydroxycinnamoylglucoside).
  • Isolated from the plant Gentiana triflora.
  • Transfers the hydroxycinnamoyl group only to the C-5 glucoside of anthocyanin.
  • Caffeoyl-CoA, but not malonyl-CoA, can substitute as an acyl donor.
 1 Q9ZWR8
Agmatine N(4)-coumaroyltransferase. [EC: 2.3.1.64]
4-coumaroyl-CoA + agmatine = CoA + N-(4-guanidinobutyl)-4- hydroxycinnamamide.
    		 1 Q9FNP9
    Anthocyanin 6''-O-malonyltransferase. [EC: 2.3.1.171]
    Malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside).
    • Acts on pelargonidin 3-O-glucoside in dahlia (Dahlia variabilis), delphinidin 3-O-glucoside, and on cyanidin 3-O-glucoside in transgenic petunia (Petunia hybrida).
    		 1 Q8GSN8
    Anthocyanidin 3-O-glucoside 6''-O-acyltransferase. [EC: 2.3.1.215]
    4-hydroxycinnamoyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-(4-hydroxycinnamoyl)-beta-D-glucoside).
    • Isolated from the plants Perilla frutescens and Gentiana triflora (clustered gentian).
    • Acts on a range of anthocyanidin 3-O-glucosides, 3,5-di-O-glucosides and cyanidin 3-rutinoside.
    • It did not act on delphinidin 3,3',7-tri-O-glucoside.
    • Recombinant Perilla frutescens enzyme could utilize caffeoyl-CoA but not malonyl-CoA as alternative acyl donor.
    		 1 Q9MBC1
    CATH-Gene3D is a Global Biodata Core Resource Learn more...