The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Erythroid Transcription Factor GATA-1, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 4132: Nuclear receptor related 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 106 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
16 G5EFF5 (/IPI) O18473 (/IPI) O54915 (/IPI) O75469 (/IPI) P10828 (/IPI) P11473 (/IPI) P13053 (/IPI) P34021 (/IPI) P37242 (/IPI) P48281 (/IPI)
(6 more)
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
15 A0A0R4IVP0 (/IDA) A0A1D5NSB5 (/IDA) A1L1Z8 (/IDA) B0V1H8 (/IDA) F1R424 (/IDA) F6P4J3 (/IDA) G5EFF5 (/IDA) O75469 (/IDA) P48281 (/IDA) Q568N6 (/IDA)
(5 more)
Thyroid hormone binding GO:0070324
Interacting selectively and non-covalently with thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.
9 P18113 (/ISS) P37242 (/ISS) P68305 (/ISS) P68306 (/ISS) Q02965 (/ISS) Q28571 (/ISS) Q91279 (/ISS) Q9PVE4 (/ISS) Q9W785 (/ISS)
Thyroid hormone receptor activity GO:0004887
Combining with thyroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
8 P37242 (/ISS) P68305 (/ISS) P68306 (/ISS) Q02965 (/ISS) Q28571 (/ISS) Q91279 (/ISS) Q9PVE4 (/ISS) Q9W785 (/ISS)
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
6 O54915 (/ISS) P34021 (/ISS) Q8SQ01 (/ISS) Q96RI1 (/ISS) Q9PTN2 (/ISS) Q9R1A7 (/ISS)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
6 G5EFF5 (/IDA) P13053 (/IDA) P18117 (/IDA) Q62685 (/IDA) Q8JHU1 (/IDA) Q96RI1 (/IDA)
RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0000981
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
5 B0V1H8 (/IDA) F1R424 (/IDA) F6P4J3 (/IDA) P34021 (/IDA) Q8JIZ9 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
5 P11473 (/IDA) P34021 (/IDA) P48281 (/IDA) Q62735 (/IDA) Q9Z0Y9 (/IDA)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
5 A0A0R4IVP0 (/IDA) A0A1D5NSB5 (/IDA) A1L1Z8 (/IDA) G5EFF5 (/IDA) Q9Z0Y9 (/IDA)
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
5 B0V1H8 (/IDA) F1R424 (/IDA) F6P4J3 (/IDA) Q62735 (/IDA) Q8JIZ9 (/IDA)
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
4 P34021 (/IDA) Q62735 (/IDA) Q96RI1 (/IDA) Q9Z0Y9 (/IDA)
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
4 P18113 (/TAS) P34021 (/TAS) Q13133 (/TAS) Q96RI1 (/TAS)
Thyroid hormone receptor activity GO:0004887
Combining with thyroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
4 P10828 (/TAS) P18117 (/TAS) P18119 (/TAS) P37242 (/TAS)
Calcitriol receptor activity GO:0008434
Combining with calcitriol, the hormonally active form of vitamin D3, and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
4 P11473 (/IDA) P13053 (/IDA) Q1L673 (/IDA) Q9PTN2 (/IDA)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
3 O75469 (/IDA) Q24143 (/IDA) Q96RI1 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
3 P10828 (/TAS) P11473 (/TAS) Q13133 (/TAS)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
3 P13053 (/TAS) P37242 (/TAS) Q96RI1 (/TAS)
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
3 O75469 (/TAS) Q13133 (/TAS) Q96RI1 (/TAS)
Thyroid hormone receptor activity GO:0004887
Combining with thyroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
3 P10828 (/IDA) P18113 (/IDA) Q9PVE4 (/IDA)
Vitamin D binding GO:0005499
Interacting selectively and non-covalently with vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
3 O42392 (/IDA) P13053 (/IDA) Q9PTN2 (/IDA)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
3 O54915 (/ISS) Q8SQ01 (/ISS) Q9R1A7 (/ISS)
Calcitriol binding GO:1902098
Interacting selectively and non-covalently with calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3.
3 P11473 (/IDA) P13053 (/IDA) Q9PTN2 (/IDA)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
2 O54915 (/ISO) Q60641 (/ISO)
RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.
2 Q62735 (/IDA) Q9Z0Y9 (/IDA)
Transcription corepressor activity GO:0003714
Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
2 P10828 (/TAS) Q96RI1 (/TAS)
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
2 O54915 (/ISO) Q60641 (/ISO)
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
2 P34021 (/NAS) Q24143 (/NAS)
Bile acid binding GO:0032052
Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile.
2 Q568N6 (/IDA) Q62735 (/IDA)
Bile acid receptor activity GO:0038181
Combining with a bile acid and transmitting the signal to initiate a change in cell activity. A bile acid is any member of a group of steroid carboxylic acids occurring in bile.
2 Q62735 (/IDA) Q96RI1 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 Q4TU03 (/ISS) Q5E9B6 (/ISS)
Retinoid X receptor binding GO:0046965
Interacting selectively and non-covalently with a retinoid X receptor.
2 P11473 (/IPI) Q62685 (/IPI)
Retinoid X receptor binding GO:0046965
Interacting selectively and non-covalently with a retinoid X receptor.
2 Q4TU03 (/ISS) Q5E9B6 (/ISS)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
2 P34021 (/IDA) Q62685 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
2 P18117 (/IPI) P34021 (/IPI)
Thyroid hormone binding GO:0070324
Interacting selectively and non-covalently with thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.
2 P10828 (/IDA) P18117 (/IDA)
Lithocholic acid binding GO:1902121
Interacting selectively and non-covalently with lithocholic acid.
2 P11473 (/IDA) Q9PTN2 (/IDA)
Sequence-specific double-stranded DNA binding GO:1990837
Interacting selectively and non-covalently with double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.
2 F1NWE9 (/IDA) P68306 (/IDA)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
1 P34021 (/IDA)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
1 Q96RI1 (/IMP)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
1 Q60641 (/ISO)
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
1 Q96RI1 (/IDA)
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
1 Q60641 (/ISO)
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1 P34021 (/IDA)
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1 P34021 (/IMP)
Transcription factor activity, RNA polymerase II transcription factor binding GO:0001076
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
1 Q9PVE4 (/IDA)
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1 Q60641 (/ISO)
Transcriptional activator activity, RNA polymerase II transcription factor binding GO:0001190
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to increase the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
1 Q96RI1 (/IDA)
Transcriptional activator activity, RNA polymerase II transcription factor binding GO:0001190
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to increase the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
1 Q60641 (/ISO)
RNA polymerase II transcription coactivator binding GO:0001225
Interacting selectively and non-covalently with an RNA polymerase II transcription coactivator, any protein involved in positive regulation of transcription of RNA polymerase II via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery of RNA polymerase II.
1 P34021 (/IPI)
Transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0001228
Interacting selectively and non-covalently with a sequence of DNA that is in the transcription regulatory region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1 O75469 (/IDA)
Transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0001228
Interacting selectively and non-covalently with a sequence of DNA that is in the transcription regulatory region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1 O54915 (/ISO)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 P48281 (/ISO)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 P34021 (/NAS)
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
1 P18113 (/IDA)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 Q60641 (/IGI)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 P10828 (/NAS)
Transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003705
Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II.
1 Q96RI1 (/IDA)
Transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003705
Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II.
1 Q60641 (/ISO)
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
1 Q62685 (/TAS)
Receptor activity GO:0004872
Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
1 Q62735 (/IDA)
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
1 Q60641 (/IMP)
Ecdysteroid hormone receptor activity GO:0004884
Combining with an ecdysteroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
1 P34021 (/IDA)
Thyroid hormone receptor activity GO:0004887
Combining with thyroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
1 P18117 (/IC)
Thyroid hormone receptor activity GO:0004887
Combining with thyroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
1 P37242 (/IMP)
Thyroid hormone receptor activity GO:0004887
Combining with thyroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
1 P37242 (/ISO)
Receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 P34021 (/IPI)
Steroid binding GO:0005496
Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
1 P34021 (/NAS)
Vitamin D binding GO:0005499
Interacting selectively and non-covalently with vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
1 P13053 (/IMP)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
1 Q9PTN2 (/IPI)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 O75469 (/IDA)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 O54915 (/ISO)
Calcitriol receptor activity GO:0008434
Combining with calcitriol, the hormonally active form of vitamin D3, and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
1 P48281 (/ISO)
Cholesterol binding GO:0015485
Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
1 Q13133 (/TAS)
Ligand-dependent nuclear receptor binding GO:0016922
Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein.
1 Q96RI1 (/TAS)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 P10828 (/IPI)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 P37242 (/ISO)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
1 P37242 (/IDA)
Bile acid binding GO:0032052
Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile.
1 Q60641 (/IMP)
Bile acid binding GO:0032052
Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile.
1 Q62735 (/IPI)
Bile acid binding GO:0032052
Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile.
1 Q96RI1 (/ISS)
Bile acid binding GO:0032052
Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile.
1 Q96RI1 (/TAS)
Sterol response element binding GO:0032810
Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism.
1 Q13133 (/IDA)
Sterol response element binding GO:0032810
Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism.
1 Q9Z0Y9 (/ISO)
Ecdysone binding GO:0035100
Interacting selectively and non-covalently with 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting.
1 P34021 (/IDA)
Enhancer binding GO:0035326
Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
1 Q8JHU1 (/IDA)
Bile acid receptor activity GO:0038181
Combining with a bile acid and transmitting the signal to initiate a change in cell activity. A bile acid is any member of a group of steroid carboxylic acids occurring in bile.
1 Q60641 (/IC)
Bile acid receptor activity GO:0038181
Combining with a bile acid and transmitting the signal to initiate a change in cell activity. A bile acid is any member of a group of steroid carboxylic acids occurring in bile.
1 Q60641 (/ISO)
Bile acid receptor activity GO:0038181
Combining with a bile acid and transmitting the signal to initiate a change in cell activity. A bile acid is any member of a group of steroid carboxylic acids occurring in bile.
1 Q96RI1 (/TAS)
Lithocholic acid receptor activity GO:0038186
Combining with lithocholic acid and transmitting the signal to initiate a change in cell activity.
1 P11473 (/IDA)
Lithocholic acid receptor activity GO:0038186
Combining with lithocholic acid and transmitting the signal to initiate a change in cell activity.
1 P48281 (/ISO)
Peptide binding GO:0042277
Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.
1 Q62735 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P18113 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P34021 (/IMP)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 P18117 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 Q60641 (/ISO)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1 Q13133 (/IDA)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1 Q9Z0Y9 (/ISO)
Retinoid X receptor binding GO:0046965
Interacting selectively and non-covalently with a retinoid X receptor.
1 Q60641 (/IDA)
Retinoid X receptor binding GO:0046965
Interacting selectively and non-covalently with a retinoid X receptor.
1 P48281 (/ISO)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 P34021 (/IMP)
Thyroid hormone binding GO:0070324
Interacting selectively and non-covalently with thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.
1 P37242 (/ISO)
Repressing transcription factor binding GO:0070491
Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription.
1 P34021 (/IPI)
Calcitriol binding GO:1902098
Interacting selectively and non-covalently with calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3.
1 P48281 (/ISO)
Lithocholic acid binding GO:1902121
Interacting selectively and non-covalently with lithocholic acid.
1 P48281 (/ISO)
Chenodeoxycholic acid binding GO:1902122
Interacting selectively and non-covalently with chenodeoxycholic acid.
1 Q96RI1 (/IDA)
Chenodeoxycholic acid binding GO:1902122
Interacting selectively and non-covalently with chenodeoxycholic acid.
1 Q60641 (/ISO)

There are 309 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
9 B0V1H8 (/IDA) F1R424 (/IDA) F6P4J3 (/IDA) P48281 (/IDA) Q568N6 (/IDA) Q8JIZ9 (/IDA) Q9PTN2 (/IDA) Q9PVE4 (/IDA) Q9Z0Y9 (/IDA)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
9 G5EFF5 (/IDA) O75469 (/IDA) P18117 (/IDA) Q13133 (/IDA) Q60641 (/IDA) Q62735 (/IDA) Q8JHU1 (/IDA) Q96RI1 (/IDA) Q9Z0Y9 (/IDA)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
7 G5EFF5 (/IMP) P11473 (/IMP) P34021 (/IMP) Q13133 (/IMP) Q60641 (/IMP) Q62735 (/IMP) Q96RI1 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
6 O54915 (/ISS) Q5BIS6 (/ISS) Q5E9B6 (/ISS) Q62685 (/ISS) Q8SQ01 (/ISS) Q9R1A7 (/ISS)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
5 B0V1H8 (/IDA) F1R424 (/IDA) F6P4J3 (/IDA) Q8JIZ9 (/IDA) Q9PTN2 (/IDA)
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
5 O75469 (/TAS) P10828 (/TAS) P11473 (/TAS) Q13133 (/TAS) Q96RI1 (/TAS)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
5 A0A060VSG9 (/IMP) A0A060WYW4 (/IMP) B8Y3M1 (/IMP) O54915 (/IMP) P11473 (/IMP)
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
4 A0A0R4IVP0 (/IDA) A0A1D5NSB5 (/IDA) A1L1Z8 (/IDA) Q24143 (/IDA)
Transcription from RNA polymerase II promoter GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
4 B0V1H8 (/IDA) F1R424 (/IDA) F6P4J3 (/IDA) Q8JIZ9 (/IDA)
Response to toxic substance GO:0009636
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
4 B0V1H8 (/IDA) F1R424 (/IDA) F6P4J3 (/IDA) Q8JIZ9 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
4 O75469 (/IDA) P11473 (/IDA) P18117 (/IDA) P37242 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
4 A5J0K7 (/IMP) P34021 (/IMP) Q13133 (/IMP) Q9Z0Y9 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
4 O54915 (/ISO) P48281 (/ISO) Q60641 (/ISO) Q9Z0Y9 (/ISO)
Regulation of cholesterol homeostasis GO:2000188
Any process that modulates the frequency, rate or extent of cholesterol homeostasis.
4 Q13133 (/ISS) Q5BIS6 (/ISS) Q5E9B6 (/ISS) Q62685 (/ISS)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 P11473 (/IDA) P18117 (/IDA) Q9Z0Y9 (/IDA)
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
3 O54915 (/ISS) Q8SQ01 (/ISS) Q9R1A7 (/ISS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
3 O75469 (/TAS) P11473 (/TAS) Q96RI1 (/TAS)
Lipid catabolic process GO:0016042
The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
3 A0A060VSG9 (/IMP) A0A060WYW4 (/IMP) B8Y3M1 (/IMP)
Exogenous drug catabolic process GO:0042738
The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism.
3 O54915 (/ISS) Q8SQ01 (/ISS) Q9R1A7 (/ISS)
Xenobiotic transport GO:0042908
The directed movement of a xenobiotic, a compound foreign to living organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 O54915 (/ISS) Q8SQ01 (/ISS) Q9R1A7 (/ISS)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
3 O75469 (/IDA) P18117 (/IDA) Q13133 (/IDA)
Drug export GO:0046618
The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, out of a cell or organelle.
3 O54915 (/ISS) Q8SQ01 (/ISS) Q9R1A7 (/ISS)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 Q60641 (/IMP) Q62735 (/IMP)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 Q13133 (/ISS) Q96RI1 (/ISS)
Nitrogen catabolite activation of transcription from RNA polymerase II promoter GO:0001080
A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.
2 Q60641 (/IC) Q96RI1 (/IC)
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
2 Q1L673 (/IMP) Q9PTN2 (/IMP)
Heart jogging GO:0003146
The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis.
2 Q1L673 (/IMP) Q9PTN2 (/IMP)
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 P37242 (/IGI) Q60641 (/IGI)
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
2 P37242 (/IMP) P48281 (/IMP)
Positive regulation of cholesterol efflux GO:0010875
Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
2 Q13133 (/IDA) Q9Z0Y9 (/IDA)
Regulation of glucose metabolic process GO:0010906
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
2 P34021 (/IMP) Q24143 (/IMP)
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
2 P34021 (/IMP) Q24143 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 O54915 (/ISO) P48281 (/ISO)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 O54915 (/ISO) Q9Z0Y9 (/ISO)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 P34021 (/IGI) P37242 (/IGI)
Triglyceride homeostasis GO:0070328
Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.
2 Q24143 (/IMP) Q9Z0Y9 (/IMP)
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
2 Q13133 (/IDA) Q9Z0Y9 (/IDA)
Regulation of cholesterol homeostasis GO:2000188
Any process that modulates the frequency, rate or extent of cholesterol homeostasis.
2 Q60641 (/IMP) Q9Z0Y9 (/IMP)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P37242 (/IGI)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P48281 (/ISO)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
1 P11473 (/IMP)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
1 P48281 (/ISO)
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
1 P48281 (/IMP)
Ossification GO:0001503
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
1 Q9PTN2 (/IMP)
Thyroid hormone mediated signaling pathway GO:0002154
A series of molecular signals mediated by the detection of a thyroid hormone.
1 Q9PVE4 (/IMP)
Regulation of carbohydrate metabolic process GO:0006109
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
1 Q62735 (/IMP)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
1 P10828 (/TAS)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 Q96RI1 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 Q60641 (/ISO)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 P37242 (/TAS)
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P34021 (/IMP)
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P13053 (/TAS)
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
1 Q62685 (/IEP)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
1 Q9Z0Y9 (/TAS)
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
1 O75469 (/IDA)
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
1 O54915 (/ISO)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P48281 (/IMP)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 O42392 (/TAS)
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
1 P48281 (/IMP)
Phagocytosis, engulfment GO:0006911
The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.
1 P34021 (/IMP)
Autophagy GO:0006914
The process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
1 P34021 (/IMP)
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
1 G5EFF5 (/IGI)
Cell-cell junction assembly GO:0007043
The aggregation, arrangement and bonding together of a set of components to form a junction between cells.
1 Q60641 (/IMP)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
1 P34021 (/IMP)
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 Q60641 (/IDA)
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
1 P48281 (/IMP)
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
1 P34021 (/IMP)
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
1 P34021 (/IMP)
Sperm individualization GO:0007291
The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane.
1 P34021 (/IMP)
Border follicle cell migration GO:0007298
The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.
1 P34021 (/IMP)
Germ-band shortening GO:0007390
The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo.
1 P34021 (/IMP)
Negative regulation of neuroblast proliferation GO:0007406
Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts.
1 P34021 (/IMP)
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
1 P34021 (/IMP)
Malpighian tubule morphogenesis GO:0007443
The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.
1 P34021 (/IMP)
Regulation of rhodopsin gene expression GO:0007468
Any process that modulates the frequency, rate or extent of rhodopsin gene expression. This includes transcriptional, translational, or posttranslational regulation.
1 P34021 (/IMP)
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
1 P34021 (/IGI)
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
1 P34021 (/IMP)
Histoblast morphogenesis GO:0007488
The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen.
1 P34021 (/IMP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 P13053 (/IEP)
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
1 P34021 (/IMP)
Metamorphosis GO:0007552
A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster.
1 P34021 (/IMP)
Imaginal disc eversion GO:0007561
The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis.
1 P34021 (/TAS)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
1 P13053 (/IEP)
Lactation GO:0007595
The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young.
1 P48281 (/IMP)
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
1 P37242 (/IMP)
Long-term memory GO:0007616
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
1 P34021 (/IMP)
Negative regulation of female receptivity GO:0007621
Any process that stops, prevents or reduces the receptiveness of a female to male advances.
1 P37242 (/IMP)
Regulation of heart contraction GO:0008016
Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.
1 P37242 (/IMP)
Female courtship behavior GO:0008050
The behavior of a female, for the purpose of attracting a sexual partner.
1 P37242 (/IMP)
Steroid metabolic process GO:0008202
The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
1 O75469 (/TAS)
Bile acid metabolic process GO:0008206
The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
1 Q62735 (/IDA)
Bile acid metabolic process GO:0008206
The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
1 Q60641 (/IMP)
Head involution GO:0008258
Movement of the anterior ectoderm to the interior of the embryo.
1 P34021 (/IMP)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 P18113 (/IMP)
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 P11473 (/IDA)
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 P48281 (/ISO)
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
1 Q62685 (/IEP)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 G5EFF5 (/IGI)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 P34021 (/IMP)
Chitin-based embryonic cuticle biosynthetic process GO:0008362
Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster.
1 P34021 (/IMP)
Epidermis development GO:0008544
The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.
1 P34021 (/IMP)
Detection of chemical stimulus GO:0009593
The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal.
1 G5EFF5 (/IGI)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
1 Q62735 (/IEP)
Cardioblast differentiation GO:0010002
The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
1 P34021 (/IMP)
Response to inorganic substance GO:0010035
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
1 G5EFF5 (/IGI)
Heat acclimation GO:0010286
Any process that increases heat tolerance of an organism in response to high temperatures.
1 G5EFF5 (/IGI)
Regulation of autophagy GO:0010506
Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
1 P34021 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P48281 (/ISO)
Negative regulation of macrophage derived foam cell differentiation GO:0010745
Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
1 Q13133 (/IC)
Negative regulation of tumor necrosis factor-mediated signaling pathway GO:0010804
Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.
1 Q60641 (/IMP)
Negative regulation of keratinocyte proliferation GO:0010839
Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
1 P11473 (/IMP)
Negative regulation of keratinocyte proliferation GO:0010839
Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
1 P48281 (/ISO)
Positive regulation of triglyceride biosynthetic process GO:0010867
Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
1 Q13133 (/IMP)
Positive regulation of triglyceride biosynthetic process GO:0010867
Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
1 Q9Z0Y9 (/ISO)
Positive regulation of receptor biosynthetic process GO:0010870
Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 Q13133 (/IDA)
Positive regulation of receptor biosynthetic process GO:0010870
Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 Q9Z0Y9 (/ISO)
Positive regulation of cholesterol efflux GO:0010875
Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
1 Q13133 (/IMP)
Positive regulation of cholesterol efflux GO:0010875
Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
1 Q9Z0Y9 (/ISO)
Negative regulation of cholesterol storage GO:0010887
Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
1 Q9Z0Y9 (/IGI)
Negative regulation of cholesterol storage GO:0010887
Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
1 Q13133 (/IMP)
Negative regulation of cholesterol storage GO:0010887
Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
1 Q9Z0Y9 (/ISO)
Positive regulation of vitamin D 24-hydroxylase activity GO:0010980
Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.
1 P11473 (/IDA)
Positive regulation of vitamin D 24-hydroxylase activity GO:0010980
Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.
1 P48281 (/ISO)
Regulation of low-density lipoprotein particle clearance GO:0010988
Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
1 Q96RI1 (/IDA)
Regulation of low-density lipoprotein particle clearance GO:0010988
Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
1 Q60641 (/ISO)
Bile acid and bile salt transport GO:0015721
The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q96RI1 (/TAS)
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
1 P34021 (/IGI)
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
1 P34021 (/IMP)
Neuron remodeling GO:0016322
The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.
1 P34021 (/IMP)
Ecdysis, chitin-based cuticle GO:0018990
The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster.
1 P34021 (/IMP)
Regulation of lipid metabolic process GO:0019216
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
1 P18113 (/IDA)
Intracellular receptor signaling pathway GO:0030522
Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.
1 Q60641 (/IMP)
Intracellular receptor signaling pathway GO:0030522
Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.
1 Q96RI1 (/ISS)
Negative regulation of NF-kappaB transcription factor activity GO:0032088
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
1 Q60641 (/IMP)
Positive regulation of cellular protein metabolic process GO:0032270
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
1 Q13133 (/IMP)
Positive regulation of cellular protein metabolic process GO:0032270
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
1 Q9Z0Y9 (/ISO)
Positive regulation of chondrocyte differentiation GO:0032332
Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.
1 P18113 (/IDA)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
1 P13053 (/IEP)
Negative regulation of lipid transport GO:0032369
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q13133 (/IMP)
Negative regulation of lipid transport GO:0032369
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9Z0Y9 (/ISO)
Positive regulation of cholesterol transport GO:0032376
Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q13133 (/IDA)
Positive regulation of cholesterol transport GO:0032376
Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9Z0Y9 (/ISO)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 Q62735 (/IEP)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
1 Q13133 (/IDA)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
1 Q9Z0Y9 (/ISO)
Negative regulation of interferon-gamma production GO:0032689
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
1 Q60641 (/IMP)
Negative regulation of interleukin-1 production GO:0032692
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production.
1 Q60641 (/IMP)
Negative regulation of interleukin-2 production GO:0032703
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production.
1 Q60641 (/IMP)
Negative regulation of interleukin-6 production GO:0032715
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.
1 Q60641 (/IDA)
Negative regulation of tumor necrosis factor production GO:0032720
Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
1 Q60641 (/IMP)
Response to vitamin D GO:0033280
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
1 O42392 (/TAS)
Toll-like receptor 4 signaling pathway GO:0034142
Any series of molecular signals generated as a consequence of binding to toll-like receptor 4.
1 Q96RI1 (/IDA)
Toll-like receptor 4 signaling pathway GO:0034142
Any series of molecular signals generated as a consequence of binding to toll-like receptor 4.
1 Q60641 (/ISO)
Positive regulation of toll-like receptor 4 signaling pathway GO:0034145
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
1 Q13133 (/IDA)
Positive regulation of toll-like receptor 4 signaling pathway GO:0034145
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
1 Q9Z0Y9 (/ISO)
Toll-like receptor 9 signaling pathway GO:0034162
Any series of molecular signals generated as a consequence of binding to toll-like receptor 9.
1 Q60641 (/IMP)
Regulation of urea metabolic process GO:0034255
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea.
1 Q60641 (/IMP)
Regulation of urea metabolic process GO:0034255
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea.
1 Q96RI1 (/ISS)
Histone H3-R17 methylation GO:0034971
The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone.
1 Q96RI1 (/IDA)
Histone H3-R17 methylation GO:0034971
The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone.
1 Q60641 (/ISO)
Dorsal vessel heart proper cell fate commitment GO:0035053
The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster.
1 P34021 (/IMP)
Salivary gland cell autophagic cell death GO:0035071
The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis.
1 P34021 (/IMP)
Ecdysone-mediated induction of salivary gland cell autophagic cell death GO:0035072
Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis.
1 P34021 (/NAS)
Pupariation GO:0035073
The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis.
1 P34021 (/IMP)
Response to ecdysone GO:0035075
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.
1 P34021 (/IMP)
Ecdysone receptor-mediated signaling pathway GO:0035076
The series of molecular signals generated by ecdysone binding to the ecdysone receptor complex.
1 P34021 (/IMP)
Larval wandering behavior GO:0035180
The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction.
1 P34021 (/IMP)
Hatching GO:0035188
The emergence of an immature organism from a protective structure.
1 P34021 (/IMP)
Larval central nervous system remodeling GO:0035193
Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster.
1 P34021 (/IMP)
Larval central nervous system remodeling GO:0035193
Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster.
1 P34021 (/TAS)
Regulation of hemocyte proliferation GO:0035206
Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.
1 P34021 (/IMP)
Regulation of Malpighian tubule diameter GO:0035297
Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells.
1 P34021 (/IMP)
Cellular triglyceride homeostasis GO:0035356
Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment.
1 Q96RI1 (/IDA)
Cellular triglyceride homeostasis GO:0035356
Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment.
1 Q60641 (/ISO)
Positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774
Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
1 Q60641 (/IMP)
Bile acid signaling pathway GO:0038183
A series of molecular signals initiated by the binding of a bile acid to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.
1 P11473 (/IDA)
Bile acid signaling pathway GO:0038183
A series of molecular signals initiated by the binding of a bile acid to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.
1 Q60641 (/IMP)
Bile acid signaling pathway GO:0038183
A series of molecular signals initiated by the binding of a bile acid to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.
1 P48281 (/ISO)
Bile acid signaling pathway GO:0038183
A series of molecular signals initiated by the binding of a bile acid to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.
1 Q96RI1 (/ISS)
Bile acid signaling pathway GO:0038183
A series of molecular signals initiated by the binding of a bile acid to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.
1 Q96RI1 (/TAS)
Intracellular bile acid receptor signaling pathway GO:0038185
A series of molecular signals initiated by a bile acid binding to an receptor located within a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 Q96RI1 (/IDA)
Intracellular bile acid receptor signaling pathway GO:0038185
A series of molecular signals initiated by a bile acid binding to an receptor located within a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 Q60641 (/ISO)
Chitin-based cuticle development GO:0040003
Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.
1 P34021 (/IMP)
Dauer larval development GO:0040024
The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
1 G5EFF5 (/IMP)
Regulation of development, heterochronic GO:0040034
Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached.
1 G5EFF5 (/IMP)
Regulation of development, heterochronic GO:0040034
Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached.
1 P34021 (/TAS)
Response to cocaine GO:0042220
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.
1 P34021 (/IGI)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
1 Q60641 (/IDA)
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
1 Q24143 (/IMP)
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
1 Q9Z0Y9 (/IGI)
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
1 Q13133 (/ISS)
Exogenous drug catabolic process GO:0042738
The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism.
1 O75469 (/IDA)
Exogenous drug catabolic process GO:0042738
The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism.
1 O54915 (/ISO)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
1 Q60641 (/IDA)
Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
1 Q13133 (/TAS)
Xenobiotic transport GO:0042908
The directed movement of a xenobiotic, a compound foreign to living organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 O75469 (/IDA)
Xenobiotic transport GO:0042908
The directed movement of a xenobiotic, a compound foreign to living organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 O54915 (/ISO)
Camera-type eye development GO:0043010
The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
1 Q9PVE4 (/IMP)
Negative regulation of macrophage activation GO:0043031
Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.
1 Q9Z0Y9 (/IDA)
Negative regulation of macrophage activation GO:0043031
Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.
1 Q13133 (/ISS)
Regulation of pharyngeal pumping GO:0043051
Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes.
1 G5EFF5 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
1 P34021 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q96RI1 (/IDA)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q60641 (/ISO)
Negative regulation of I-kappaB kinase/NF-kappaB signaling GO:0043124
Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.
1 Q96RI1 (/IDA)
Negative regulation of I-kappaB kinase/NF-kappaB signaling GO:0043124
Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.
1 Q60641 (/IMP)
Negative regulation of I-kappaB kinase/NF-kappaB signaling GO:0043124
Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.
1 Q60641 (/ISO)
Apoptotic cell clearance GO:0043277
The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
1 Q13133 (/IMP)
Apoptotic cell clearance GO:0043277
The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
1 Q9Z0Y9 (/ISO)
Chemotaxis to cAMP GO:0043327
The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP.
1 G5EFF5 (/IGI)
Regulation of cellular respiration GO:0043457
Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds.
1 P34021 (/IMP)
Negative regulation of growth of symbiont in host GO:0044130
Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
1 P34021 (/IMP)
Cellular lipid metabolic process GO:0044255
The chemical reactions and pathways involving lipids, as carried out by individual cells.
1 Q9Z0Y9 (/IDA)
Positive regulation of keratinocyte differentiation GO:0045618
Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation.
1 P11473 (/IMP)
Positive regulation of keratinocyte differentiation GO:0045618
Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation.
1 P48281 (/ISO)
Positive regulation of fatty acid biosynthetic process GO:0045723
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
1 Q13133 (/IMP)
Positive regulation of fatty acid biosynthetic process GO:0045723
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
1 Q9Z0Y9 (/ISO)
Positive regulation of ossification GO:0045778
Any process that activates or increases the frequency, rate or extent of bone formation.
1 P18113 (/IDA)
Negative regulation of proteolysis GO:0045861
Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
1 Q9Z0Y9 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9Z0Y9 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 P34021 (/TAS)
Positive regulation of circadian sleep/wake cycle, sleep GO:0045938
Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
1 P34021 (/IMP)
Retinal cone cell development GO:0046549
Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.
1 Q9PVE4 (/IMP)
Drug export GO:0046618
The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, out of a cell or organelle.
1 O75469 (/IDA)
Drug export GO:0046618
The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, out of a cell or organelle.
1 O54915 (/ISO)
Positive regulation of insulin receptor signaling pathway GO:0046628
Any process that increases the frequency, rate or extent of insulin receptor signaling.
1 Q60641 (/IDA)
Decidualization GO:0046697
The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.
1 P11473 (/IEP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
1 P34021 (/IMP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
1 P34021 (/NAS)
Negative regulation of pinocytosis GO:0048550
Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.
1 Q13133 (/IMP)
Negative regulation of pinocytosis GO:0048550
Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.
1 Q9Z0Y9 (/ISO)
Digestive tract development GO:0048565
The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.
1 Q62735 (/IEP)
Embryonic organ development GO:0048568
Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
1 P18113 (/IEP)
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
1 P34021 (/IMP)
Cardiac muscle tissue development GO:0048738
The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.
1 P34021 (/IMP)
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized. A dendrite is a freely branching protoplasmic process of a nerve cell.
1 P34021 (/IMP)
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized. A dendrite is a freely branching protoplasmic process of a nerve cell.
1 P34021 (/NAS)
Inner ear development GO:0048839
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
1 Q9PVE4 (/IMP)
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
1 Q9Z0Y9 (/IDA)
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
1 Q60641 (/IMP)
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
1 Q13133 (/ISS)
Intestinal absorption GO:0050892
Any process in which nutrients are taken up from the contents of the intestine.
1 P48281 (/IMP)
Positive regulation of lipoprotein lipase activity GO:0051006
Any process that activates or increases the activity of the enzyme lipoprotein lipase.
1 Q13133 (/IMP)
Positive regulation of lipoprotein lipase activity GO:0051006
Any process that activates or increases the activity of the enzyme lipoprotein lipase.
1 Q9Z0Y9 (/ISO)
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
1 P13053 (/IEP)
Regulation of calcium ion transport GO:0051924
Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P13053 (/IDA)
Calcium ion homeostasis GO:0055074
Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
1 Q9PTN2 (/IMP)
Lipid homeostasis GO:0055088
Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
1 Q9Z0Y9 (/IGI)
Lipid homeostasis GO:0055088
Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
1 Q9Z0Y9 (/IMP)
Lipid homeostasis GO:0055088
Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
1 Q13133 (/ISS)
Fatty acid homeostasis GO:0055089
Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell.
1 Q60641 (/IMP)
Sterol homeostasis GO:0055092
Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.
1 Q9Z0Y9 (/IMP)
Sterol homeostasis GO:0055092
Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.
1 Q13133 (/ISS)
Positive regulation of apoptotic process involved in mammary gland involution GO:0060058
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution.
1 P48281 (/IMP)
Inner ear receptor cell development GO:0060119
The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
1 Q1L673 (/IMP)
Male mating behavior GO:0060179
The specific behavior of a male organism that is associated with reproduction.
1 G5EFF5 (/IMP)
Negative regulation of interferon-gamma-mediated signaling pathway GO:0060336
Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.
1 Q13133 (/NAS)
Type I pneumocyte differentiation GO:0060509
The process in which a relatively unspecialized cell acquires specialized features of a Type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles.
1 P37242 (/IGI)
Regulation of calcidiol 1-monooxygenase activity GO:0060558
Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.
1 P48281 (/IMP)
Regulation of calcidiol 1-monooxygenase activity GO:0060558
Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.
1 P11473 (/ISS)
Mammary gland branching involved in pregnancy GO:0060745
The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy.
1 P48281 (/IMP)
Regulation of dauer larval development GO:0061065
Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
1 G5EFF5 (/IGI)
Positive regulation of dauer larval development GO:0061066
Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
1 G5EFF5 (/IMP)
Regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178
Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
1 Q96RI1 (/IDA)
Regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178
Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
1 Q60641 (/ISO)
Triglyceride homeostasis GO:0070328
Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.
1 Q60641 (/IDA)
Triglyceride homeostasis GO:0070328
Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.
1 Q9Z0Y9 (/IGI)
Triglyceride homeostasis GO:0070328
Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.
1 Q13133 (/ISS)
Vitamin D receptor signaling pathway GO:0070561
The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands.
1 P11473 (/IDA)
Vitamin D receptor signaling pathway GO:0070561
The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands.
1 P48281 (/ISO)
Response to biotin GO:0070781
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.
1 G5EFF5 (/IGI)
Regulation of bile acid biosynthetic process GO:0070857
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
1 Q96RI1 (/TAS)
Negative regulation of bile acid biosynthetic process GO:0070858
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
1 Q96RI1 (/IDA)
Negative regulation of bile acid biosynthetic process GO:0070858
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
1 Q60641 (/ISO)
Regulation of glycogen metabolic process GO:0070873
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.
1 Q24143 (/IMP)
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 Q60641 (/IMP)
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 Q9Z0Y9 (/ISO)
Cellular response to vitamin D GO:0071305
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
1 P13053 (/IEP)
Cellular response to type I interferon GO:0071357
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
1 A5J0K7 (/IMP)
Cellular response to fatty acid GO:0071398
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.
1 Q96RI1 (/IDA)
Cellular response to fatty acid GO:0071398
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.
1 Q60641 (/ISO)
Cellular response to organonitrogen compound GO:0071417
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
1 Q60641 (/IMP)
Cellular response to organonitrogen compound GO:0071417
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
1 Q96RI1 (/ISS)
Otic vesicle development GO:0071599
The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.
1 Q1L673 (/IMP)
Negative regulation of monocyte chemotactic protein-1 production GO:0071638
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1.
1 Q60641 (/IMP)
Interleukin-17 secretion GO:0072615
The regulated release of any member of the interleukin-17 family of cytokines from a cell.
1 Q96RI1 (/IDA)
Interleukin-17 secretion GO:0072615
The regulated release of any member of the interleukin-17 family of cytokines from a cell.
1 Q60641 (/ISO)
Regulation of cholesterol metabolic process GO:0090181
Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
1 P18113 (/IMP)
Regulation of cholesterol metabolic process GO:0090181
Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
1 Q96RI1 (/TAS)
Negative regulation of pancreatic juice secretion GO:0090188
Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
1 Q9Z0Y9 (/IMP)
Negative regulation of pancreatic juice secretion GO:0090188
Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
1 Q13133 (/ISS)
Regulation of triglyceride metabolic process GO:0090207
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.
1 P18113 (/IMP)
Negative regulation of secretion of lysosomal enzymes GO:0090341
Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
1 Q9Z0Y9 (/IMP)
Negative regulation of secretion of lysosomal enzymes GO:0090341
Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
1 Q13133 (/ISS)
Apoptotic signaling pathway GO:0097190
A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
1 P13053 (/IDA)
Negative regulation of interferon-gamma secretion GO:1902714
Any process that stops, prevents or reduces the frequency, rate or extent of interferon-gamma secretion.
1 Q96RI1 (/IDA)
Negative regulation of interferon-gamma secretion GO:1902714
Any process that stops, prevents or reduces the frequency, rate or extent of interferon-gamma secretion.
1 Q60641 (/ISO)
Positive regulation of adipose tissue development GO:1904179
Any process that activates or increases the frequency, rate or extent of adipose tissue development.
1 Q60641 (/IMP)
Negative regulation of tumor necrosis factor secretion GO:1904468
Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor secretion.
1 Q96RI1 (/IDA)
Negative regulation of tumor necrosis factor secretion GO:1904468
Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor secretion.
1 Q60641 (/ISO)
Regulation of neuron remodeling GO:1904799
Any process that modulates the frequency, rate or extent of neuron remodeling.
1 P34021 (/IMP)
Positive regulation of phosphatidic acid biosynthetic process GO:1905695
Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process.
1 Q96RI1 (/IDA)
Positive regulation of phosphatidic acid biosynthetic process GO:1905695
Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process.
1 Q60641 (/ISO)
Positive regulation of cholesterol homeostasis GO:2000189
Any process that activates or increases the frequency, rate or extent of cholesterol homeostasis.
1 Q13133 (/IDA)
Positive regulation of cholesterol homeostasis GO:2000189
Any process that activates or increases the frequency, rate or extent of cholesterol homeostasis.
1 Q9Z0Y9 (/ISO)
Positive regulation of glutamate metabolic process GO:2000213
Any process that activates or increases the frequency, rate or extent of glutamate metabolic process.
1 Q60641 (/IMP)
Positive regulation of glutamate metabolic process GO:2000213
Any process that activates or increases the frequency, rate or extent of glutamate metabolic process.
1 Q96RI1 (/ISS)
Positive regulation of ammonia assimilation cycle GO:2001250
Any process that activates or increases the frequency, rate or extent of ammonia assimilation cycle.
1 Q60641 (/IMP)
Positive regulation of glucose import in response to insulin stimulus GO:2001275
Any process that activates or increases the frequency, rate or extent of glucose import in response to insulin stimulus.
1 Q60641 (/IDA)

There are 45 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
13 F1NWE9 (/IDA) F5GWT5 (/IDA) G5EFF5 (/IDA) O42392 (/IDA) P11473 (/IDA) P18117 (/IDA) P34021 (/IDA) P37242 (/IDA) P68306 (/IDA) Q13133 (/IDA)
(3 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
7 F1D8P8 (/IDA) F1D8P9 (/IDA) F8VRJ4 (/IDA) H0Y8E2 (/IDA) J3KPQ3 (/IDA) O75469 (/IDA) P11473 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 O42392 (/TAS) P10828 (/TAS) P18113 (/TAS) P37242 (/TAS) Q13133 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
5 O75469 (/TAS) P10828 (/TAS) P11473 (/TAS) Q13133 (/TAS) Q96RI1 (/TAS)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
4 F1D8N7 (/IDA) F1D8P9 (/IDA) O75469 (/IDA) P10828 (/IDA)
Intermediate filament cytoskeleton GO:0045111
Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.
3 F1D8P9 (/IDA) J3KPQ3 (/IDA) O75469 (/IDA)
RNA polymerase II transcription factor complex GO:0090575
A transcription factor complex that acts at promoters of genes transcribed by RNA polymerase II.
3 P11473 (/IDA) Q13133 (/IDA) Q9Z0Y9 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P48281 (/ISO) Q9Z0Y9 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 O54915 (/ISO) P48281 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P34021 (/IDA) Q62685 (/IDA)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
2 O54915 (/ISO) P37242 (/ISO)
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
2 P11473 (/IDA) Q13133 (/IDA)
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
2 P48281 (/ISO) Q9Z0Y9 (/ISO)
RNA polymerase II transcription factor complex GO:0090575
A transcription factor complex that acts at promoters of genes transcribed by RNA polymerase II.
2 P48281 (/ISO) Q9Z0Y9 (/ISO)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
1 Q13133 (/IDA)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
1 Q9Z0Y9 (/ISO)
Euchromatin GO:0000791
A dispersed and relatively uncompacted form of chromatin.
1 P13053 (/IDA)
Heterochromatin GO:0000792
A compact and highly condensed form of chromatin.
1 P13053 (/IDA)
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
1 F5GWT5 (/IDA)
Dense fibrillar component GO:0001651
A structure found in the nucleolus, which contains newly synthesized preribosomal RNA (pre-rRNA) and a collection of proteins.
1 P13053 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P34021 (/IMP)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q5E9B6 (/ISS)
Polytene chromosome GO:0005700
A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
1 P34021 (/IDA)
Polytene chromosome GO:0005700
A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
1 P34021 (/NAS)
Nuclear euchromatin GO:0005719
The dispersed less dense form of chromatin in the interphase nucleus. It exists in at least two forms, a some being in the form of transcriptionally active chromatin which is the least condensed, while the rest is inactive euchromatin which is more condensed than active chromatin but less condensed than heterochromatin.
1 Q96RI1 (/IDA)
Nuclear euchromatin GO:0005719
The dispersed less dense form of chromatin in the interphase nucleus. It exists in at least two forms, a some being in the form of transcriptionally active chromatin which is the least condensed, while the rest is inactive euchromatin which is more condensed than active chromatin but less condensed than heterochromatin.
1 Q60641 (/ISO)
Nuclear heterochromatin GO:0005720
A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin.
1 P13053 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P13053 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 O42392 (/TAS)
Caveola GO:0005901
A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis. Caveolae may be pinched off to form free vesicles within the cytoplasm.
1 O42392 (/IDA)
Ecdysone receptor holocomplex GO:0008230
A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes.
1 P34021 (/IMP)
Ecdysone receptor holocomplex GO:0008230
A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes.
1 P34021 (/IPI)
Ecdysone receptor holocomplex GO:0008230
A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes.
1 P34021 (/TAS)
Repressor ecdysone receptor complex GO:0008231
A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) plus an associated corepressor such as SMRTER, which represses transcription of target genes.
1 P34021 (/IPI)
Activator ecdysone receptor complex GO:0008232
A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) bound to the ligand ecdysone, which activates transcription of target genes.
1 P34021 (/IDA)
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
1 F5GWT5 (/IDA)
Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
1 P13053 (/IDA)
T-tubule GO:0030315
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
1 P13053 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 P34021 (/IMP)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 P13053 (/IDA)
Intermediate filament cytoskeleton GO:0045111
Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.
1 O54915 (/ISO)
Intercellular bridge GO:0045171
A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
1 F5GWT5 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 P13053 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 P10828 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 P37242 (/ISO)