The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Erythroid Transcription Factor GATA-1, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 233: Retinoic acid receptor gamma

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 60 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 D3ZFD9 (/IPI) O54746 (/IPI) P10276 (/IPI) P10826 (/IPI) P11416 (/IPI) P13631 (/IPI) P18911 (/IPI) Q15156 (/IPI) Q499N1 (/IPI)
Retinoic acid receptor activity GO:0003708
Combining with retinoic acid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. Retinoic acid is one of the forms of vitamin A.
7 A0A0G2JW78 (/IDA) D3ZFD9 (/IDA) O54746 (/IDA) P10276 (/IDA) P11416 (/IDA) Q499N1 (/IDA) Q90271 (/IDA)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
4 P10276 (/IDA) P11416 (/IDA) P18911 (/IDA) P22605 (/IDA)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
4 A0A0G2JW78 (/IPI) P10276 (/IPI) P11416 (/IPI) Q499N1 (/IPI)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
4 A0A0G2JW78 (/IDA) D3ZFD9 (/IDA) O54746 (/IDA) Q499N1 (/IDA)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
3 P11416 (/IDA) P18911 (/IDA) P22605 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
3 P11416 (/IDA) P18911 (/IDA) Q91392 (/IDA)
Retinoic acid receptor activity GO:0003708
Combining with retinoic acid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. Retinoic acid is one of the forms of vitamin A.
3 A0A0G2JW78 (/TAS) P10826 (/TAS) Q499N1 (/TAS)
Translation repressor activity, nucleic acid binding GO:0000900
Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.
2 A0A0G2JW78 (/IDA) Q499N1 (/IDA)
Retinoic acid receptor activity GO:0003708
Combining with retinoic acid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. Retinoic acid is one of the forms of vitamin A.
2 D3ZF61 (/IMP) D3ZWV0 (/IMP)
Retinoic acid receptor activity GO:0003708
Combining with retinoic acid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. Retinoic acid is one of the forms of vitamin A.
2 D3ZFD9 (/NAS) O54746 (/NAS)
Protein complex binding GO:0032403
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 D3ZFD9 (/IPI) O54746 (/IPI)
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
2 A0A0G2JW78 (/IPI) Q499N1 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 P11416 (/IDA) P22605 (/IDA)
Retinoid X receptor binding GO:0046965
Interacting selectively and non-covalently with a retinoid X receptor.
2 D3ZFD9 (/IPI) O54746 (/IPI)
MRNA 5'-UTR binding GO:0048027
Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule.
2 A0A0G2JW78 (/IDA) Q499N1 (/IDA)
Regulatory region DNA binding GO:0000975
Interacting selectively and non-covalently with a DNA region that regulates a DNA-based process. Such processes include transcription, DNA replication, and DNA repair.
1 P11416 (/IDA)
RNA polymerase II regulatory region DNA binding GO:0001012
Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by RNA polymerase II. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1 P11416 (/IDA)
Retinoic acid binding GO:0001972
Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.
1 P10276 (/IDA)
Retinoic acid binding GO:0001972
Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.
1 E7BBH7 (/IMP)
Retinoic acid binding GO:0001972
Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.
1 P11416 (/ISO)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 P13631 (/ISS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 P10826 (/TAS)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 P11416 (/ISO)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 P13631 (/ISS)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 Q15156 (/NAS)
Retinoic acid receptor activity GO:0003708
Combining with retinoic acid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. Retinoic acid is one of the forms of vitamin A.
1 P11416 (/ISO)
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
1 P10276 (/IDA)
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
1 P10276 (/IMP)
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
1 P11416 (/ISO)
Transcription corepressor activity GO:0003714
Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
1 P10276 (/IDA)
Transcription corepressor activity GO:0003714
Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
1 P11416 (/ISO)
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
1 P11416 (/IDA)
Receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 P10276 (/IDA)
Receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 P11416 (/ISO)
Retinoid binding GO:0005501
Interacting selectively and non-covalently with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
1 E7BBH7 (/IMP)
All-trans retinal binding GO:0005503
Interacting selectively and non-covalently with all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.
1 E7BBH7 (/IMP)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
1 P11416 (/ISO)
Retinol binding GO:0019841
Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.
1 E7BBH7 (/IMP)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 P10276 (/IPI)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 P11416 (/ISO)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 P10276 (/IPI)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 P11416 (/ISO)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
1 P10276 (/IDA)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
1 P11416 (/ISO)
Phosphatidylinositol 3-kinase regulator activity GO:0035014
Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates.
1 Q499N1 (/IMP)
Protein kinase B binding GO:0043422
Interacting selectively and non-covalently with protein kinase B, an intracellular kinase that is important in regulating glucose metabolism.
1 P10276 (/IPI)
Protein kinase B binding GO:0043422
Interacting selectively and non-covalently with protein kinase B, an intracellular kinase that is important in regulating glucose metabolism.
1 P11416 (/ISO)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 P11416 (/IGI)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1 P11416 (/IMP)
Retinoic acid-responsive element binding GO:0044323
Interacting selectively and non-covalently with a retinoic acid-responsive element, a variable direct repeat of the sequence PuGGTCA spaced by five nucleotides (DR5) found in the promoters of retinoic acid-responsive genes, to which retinoic acid receptors bind.
1 P10276 (/IDA)
Retinoic acid-responsive element binding GO:0044323
Interacting selectively and non-covalently with a retinoic acid-responsive element, a variable direct repeat of the sequence PuGGTCA spaced by five nucleotides (DR5) found in the promoters of retinoic acid-responsive genes, to which retinoic acid receptors bind.
1 P11416 (/ISO)
Retinoid X receptor binding GO:0046965
Interacting selectively and non-covalently with a retinoid X receptor.
1 P18911 (/IMP)
Retinoid X receptor binding GO:0046965
Interacting selectively and non-covalently with a retinoid X receptor.
1 P13631 (/ISS)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 P10276 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 P11416 (/ISO)
Protein kinase A binding GO:0051018
Interacting selectively and non-covalently with any subunit of protein kinase A.
1 P10276 (/IDA)
Protein kinase A binding GO:0051018
Interacting selectively and non-covalently with any subunit of protein kinase A.
1 P11416 (/ISO)
Alpha-actinin binding GO:0051393
Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.
1 P10276 (/IPI)
Alpha-actinin binding GO:0051393
Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.
1 P11416 (/ISO)

There are 154 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of myelination GO:0031641
Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
6 A0A0G2JW78 (/IDA) D3ZF61 (/IDA) D3ZFD9 (/IDA) D3ZWV0 (/IDA) O54746 (/IDA) Q499N1 (/IDA)
Retinoic acid receptor signaling pathway GO:0048384
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.
5 A0A0G2JW78 (/IDA) D3ZFD9 (/IDA) O54746 (/IDA) P13631 (/IDA) Q499N1 (/IDA)
Retinoic acid receptor signaling pathway GO:0048384
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.
5 D3ZF61 (/IMP) D3ZWV0 (/IMP) P10276 (/IMP) P18911 (/IMP) P51126 (/IMP)
Response to retinoic acid GO:0032526
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
4 P13631 (/IDA) P22448 (/IDA) Q90271 (/IDA) Q90966 (/IDA)
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
4 A0A0G2JW78 (/IDA) D3ZFD9 (/IDA) O54746 (/IDA) Q499N1 (/IDA)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
4 P10276 (/IDA) P11416 (/IDA) P18911 (/IDA) P22605 (/IDA)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 P11416 (/IDA) P18911 (/IDA) P22605 (/IDA)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
3 Q7ZTI3 (/IMP) Q90271 (/IMP) Q91392 (/IMP)
Glandular epithelial cell development GO:0002068
The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.
3 P11416 (/IGI) P18911 (/IGI) P22605 (/IGI)
Growth plate cartilage development GO:0003417
The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow.
3 P11416 (/IGI) P18911 (/IGI) P22605 (/IGI)
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
3 P10276 (/TAS) P10826 (/TAS) P13631 (/TAS)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
3 P11416 (/IGI) P18911 (/IGI) P22605 (/IGI)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
3 D3ZF61 (/IMP) D3ZWV0 (/IMP) P10276 (/IMP)
Multicellular organism growth GO:0035264
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
3 P11416 (/IGI) P18911 (/IGI) P22605 (/IGI)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
3 P11416 (/IGI) P18911 (/IGI) P22605 (/IGI)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 P11416 (/IGI) P18911 (/IGI) P22605 (/IGI)
Bone development GO:0060348
The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.
3 P11416 (/IGI) P18911 (/IGI) P22605 (/IGI)
Negative regulation of cartilage development GO:0061037
Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
3 P11416 (/IMP) P18911 (/IMP) P22605 (/IMP)
Ureteric bud development GO:0001657
The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.
2 P11416 (/IMP) P22605 (/IMP)
Neural tube closure GO:0001843
The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.
2 P11416 (/IGI) P18911 (/IGI)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
2 A0A0G2JW78 (/IEP) Q499N1 (/IEP)
Outflow tract septum morphogenesis GO:0003148
The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.
2 P11416 (/IGI) P22605 (/IGI)
Retinal pigment epithelium development GO:0003406
The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells.
2 P18911 (/IGI) P22605 (/IGI)
Female pregnancy GO:0007565
The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.
2 A0A0G2JW78 (/IEP) Q499N1 (/IEP)
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
2 A0A0G2JW78 (/IDA) Q499N1 (/IDA)
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
2 P18911 (/IGI) P22605 (/IGI)
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
2 A0A0G2JW78 (/IDA) Q499N1 (/IDA)
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
2 A0A0G2JW78 (/IDA) Q499N1 (/IDA)
Hindbrain morphogenesis GO:0021575
The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.
2 Q90271 (/IDA) Q90966 (/IDA)
Hippocampus development GO:0021766
The progression of the hippocampus over time from its initial formation until its mature state.
2 A0A0G2JW78 (/IEP) Q499N1 (/IEP)
Prostate gland development GO:0030850
The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.
2 A0A0G2JW78 (/IEP) Q499N1 (/IEP)
Embryonic camera-type eye development GO:0031076
The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.
2 P11416 (/IGI) P18911 (/IGI)
Negative regulation of chondrocyte differentiation GO:0032331
Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation.
2 P18911 (/IMP) P22605 (/IMP)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
2 A0A0G2JW78 (/IEP) Q499N1 (/IEP)
Response to retinoic acid GO:0032526
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
2 P10276 (/IMP) P11416 (/IMP)
Response to retinoic acid GO:0032526
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
2 P11416 (/ISO) P18911 (/ISO)
Response to vitamin A GO:0033189
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.
2 A0A0G2JW78 (/IEP) Q499N1 (/IEP)
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
2 A0A0G2JW78 (/IEP) Q499N1 (/IEP)
Embryonic hindlimb morphogenesis GO:0035116
The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.
2 P18911 (/IGI) P22605 (/IGI)
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
2 A0A0G2JW78 (/IDA) Q499N1 (/IDA)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
2 P18911 (/IGI) P22605 (/IGI)
Positive regulation of programmed cell death GO:0043068
Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
2 P18911 (/IGI) P22605 (/IGI)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
2 A0A0G2JW78 (/IDA) Q499N1 (/IDA)
Negative regulation of cell differentiation GO:0045596
Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
2 P11416 (/IMP) P18911 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 P10276 (/IDA) P11416 (/IDA)
Embryonic eye morphogenesis GO:0048048
The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized.
2 P18911 (/IGI) P22605 (/IGI)
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
2 A0A0G2JW78 (/IDA) Q499N1 (/IDA)
Retinoic acid receptor signaling pathway GO:0048384
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.
2 P11416 (/ISO) P18911 (/ISO)
Ventricular cardiac muscle cell differentiation GO:0055012
The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.
2 P11416 (/IMP) P22605 (/IMP)
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
2 P18911 (/IGI) P22605 (/IGI)
Limb development GO:0060173
The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.
2 P11416 (/IGI) P18911 (/IGI)
Face development GO:0060324
The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head.
2 P11416 (/IGI) P18911 (/IGI)
Trachea cartilage development GO:0060534
The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
2 P11416 (/IMP) P18911 (/IMP)
Cellular response to retinoic acid GO:0071300
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
2 P10276 (/IDA) P18911 (/IDA)
Cellular response to retinoic acid GO:0071300
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
2 D3ZF61 (/IEP) D3ZWV0 (/IEP)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P11416 (/IGI)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P13631 (/ISS)
Chondrocyte development GO:0002063
The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.
1 P18911 (/IMP)
Determination of left/right asymmetry in lateral mesoderm GO:0003140
The establishment of the lateral mesoderm with respect to the left and right halves.
1 A2T928 (/IMP)
Growth plate cartilage chondrocyte growth GO:0003430
The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another.
1 P18911 (/IMP)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
1 P51126 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 P11416 (/IDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 P10276 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 P11416 (/ISO)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 P10276 (/IDA)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 P11416 (/ISO)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 P10826 (/TAS)
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
1 P11416 (/IMP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 P11416 (/IMP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 Q7ZTI3 (/IGI)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 Q7ZTI3 (/IMP)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 P11416 (/ISO)
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 P13631 (/ISS)
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
1 P13631 (/TAS)
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
1 P18911 (/IGI)
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
1 P18911 (/IMP)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P18911 (/IGI)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P18911 (/IDA)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P11416 (/IMP)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P11416 (/IGI)
Positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
1 Q499N1 (/IMP)
Striatum development GO:0021756
The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.
1 P22605 (/IMP)
Central nervous system neuron axonogenesis GO:0021955
Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells.
1 P51126 (/IMP)
Neurogenesis GO:0022008
Generation of cells within the nervous system.
1 P22605 (/IMP)
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
1 A2T928 (/IMP)
Regulation of granulocyte differentiation GO:0030852
Any process that modulates the frequency, rate or extent of granulocyte differentiation.
1 P11416 (/IMP)
Negative regulation of granulocyte differentiation GO:0030853
Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation.
1 P10276 (/IDA)
Negative regulation of granulocyte differentiation GO:0030853
Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation.
1 P11416 (/ISO)
Midbrain-hindbrain boundary development GO:0030917
The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.
1 Q7ZTI3 (/IGI)
Negative regulation of interferon-gamma production GO:0032689
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
1 P10276 (/IDA)
Negative regulation of interferon-gamma production GO:0032689
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
1 P11416 (/ISO)
Negative regulation of tumor necrosis factor production GO:0032720
Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
1 P10276 (/IDA)
Negative regulation of tumor necrosis factor production GO:0032720
Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
1 P11416 (/ISO)
Positive regulation of interleukin-13 production GO:0032736
Any process that activates or increases the frequency, rate, or extent of interleukin-13 production.
1 P10276 (/IDA)
Positive regulation of interleukin-13 production GO:0032736
Any process that activates or increases the frequency, rate, or extent of interleukin-13 production.
1 P11416 (/ISO)
Positive regulation of interleukin-4 production GO:0032753
Any process that activates or increases the frequency, rate, or extent of interleukin-4 production.
1 P10276 (/IDA)
Positive regulation of interleukin-4 production GO:0032753
Any process that activates or increases the frequency, rate, or extent of interleukin-4 production.
1 P11416 (/ISO)
Positive regulation of interleukin-5 production GO:0032754
Any process that activates or increases the frequency, rate, or extent of interleukin-5 production.
1 P10276 (/IDA)
Positive regulation of interleukin-5 production GO:0032754
Any process that activates or increases the frequency, rate, or extent of interleukin-5 production.
1 P11416 (/ISO)
Pectoral fin development GO:0033339
The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.
1 Q7ZTI3 (/IDA)
Limb morphogenesis GO:0035108
The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.
1 P22448 (/IDA)
Embryonic hindlimb morphogenesis GO:0035116
The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.
1 P13631 (/ISS)
Determination of pancreatic left/right asymmetry GO:0035469
Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism.
1 A2T928 (/IMP)
Intrahepatic bile duct development GO:0035622
The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).
1 A2T928 (/IMP)
Camera-type eye development GO:0043010
The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
1 P18911 (/IGI)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
1 P13631 (/ISS)
Positive regulation of programmed cell death GO:0043068
Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
1 P13631 (/ISS)
Apoptotic cell clearance GO:0043277
The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
1 P10276 (/IMP)
Apoptotic cell clearance GO:0043277
The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
1 P11416 (/ISO)
Positive regulation of T-helper 2 cell differentiation GO:0045630
Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation.
1 P10276 (/IDA)
Positive regulation of T-helper 2 cell differentiation GO:0045630
Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation.
1 P11416 (/ISO)
Regulation of myeloid cell differentiation GO:0045637
Any process that modulates the frequency, rate or extent of myeloid cell differentiation.
1 P18911 (/IGI)
Positive regulation of cell cycle GO:0045787
Any process that activates or increases the rate or extent of progression through the cell cycle.
1 P10276 (/IMP)
Positive regulation of cell cycle GO:0045787
Any process that activates or increases the rate or extent of progression through the cell cycle.
1 P11416 (/ISO)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 P11416 (/ISO)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 P10276 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 P10276 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 P11416 (/ISO)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P18911 (/IC)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P10276 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P11416 (/ISO)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P13631 (/ISS)
Negative regulation of translational initiation GO:0045947
Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.
1 P11416 (/IDA)
Embryonic eye morphogenesis GO:0048048
The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized.
1 P13631 (/ISS)
Embryonic digestive tract development GO:0048566
The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus.
1 P10826 (/IMP)
Embryonic digestive tract development GO:0048566
The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus.
1 P22605 (/ISO)
Reproductive structure development GO:0048608
The reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.
1 P18911 (/IMP)
Gland development GO:0048732
The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.
1 P18911 (/IMP)
Positive regulation of neurogenesis GO:0050769
Any process that activates or increases the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
1 P51126 (/IMP)
Positive regulation of binding GO:0051099
Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
1 P10276 (/IMP)
Positive regulation of binding GO:0051099
Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
1 P11416 (/ISO)
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
1 Q499N1 (/IMP)
Sertoli cell fate commitment GO:0060010
The process in which the cellular identity of Sertoli cells is acquired and determined.
1 P11416 (/IMP)
Pharyngeal system development GO:0060037
The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.
1 Q91392 (/IDA)
Canonical Wnt signaling pathway GO:0060070
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
1 P13631 (/TAS)
Limb development GO:0060173
The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.
1 P18911 (/IMP)
Bone development GO:0060348
The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.
1 P18911 (/IMP)
Bone morphogenesis GO:0060349
The process in which bones are generated and organized.
1 P18911 (/IGI)
Bone morphogenesis GO:0060349
The process in which bones are generated and organized.
1 P18911 (/IMP)
Epithelium development GO:0060429
The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
1 P18911 (/IMP)
Chondroblast differentiation GO:0060591
The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes.
1 P11416 (/IMP)
Prostate gland epithelium morphogenesis GO:0060740
The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
1 P18911 (/IMP)
Determination of heart left/right asymmetry GO:0061371
Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.
1 A2T928 (/IMP)
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
1 Q499N1 (/IMP)
Harderian gland development GO:0070384
The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species.
1 P18911 (/IMP)
Inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration GO:0070660
Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury.
1 P22448 (/NAS)
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 P11416 (/IDA)
Cellular response to retinoic acid GO:0071300
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
1 P11416 (/ISO)
Cellular response to estrogen stimulus GO:0071391
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 P10276 (/IDA)
Cellular response to estrogen stimulus GO:0071391
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 P11416 (/ISO)
Beak morphogenesis GO:0071729
The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.
1 P22448 (/IDA)
Determination of digestive tract left/right asymmetry GO:0071907
Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed.
1 A2T928 (/IMP)
Determination of liver left/right asymmetry GO:0071910
Determination of the asymmetric location of the liver with respect to the left and right halves of the organism.
1 A2T928 (/IMP)
Negative regulation of extrinsic apoptotic signaling pathway GO:2001237
Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway.
1 Q15156 (/IMP)

There are 24 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
13 A0A0G2JW78 (/IDA) A8MUP8 (/IDA) D3ZFD9 (/IDA) E7BBH7 (/IDA) F1D8N9 (/IDA) O54746 (/IDA) P10276 (/IDA) P10826 (/IDA) P11416 (/IDA) P13631 (/IDA)
(3 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
6 P10276 (/TAS) P10826 (/TAS) P11416 (/TAS) P13631 (/TAS) P18911 (/TAS) P22605 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 A8MUP8 (/IDA) E7BBH7 (/IDA) F1D8N9 (/IDA) P10276 (/IDA) Q6I9R7 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 A8K3H3 (/IDA) F1D8S6 (/IDA) P10826 (/IDA) P13631 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 A0A0G2JW78 (/IDA) P10276 (/IDA) P11416 (/IDA) Q499N1 (/IDA)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
4 A8MUP8 (/IDA) F1D8N9 (/IDA) P10276 (/IDA) Q6I9R7 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P11416 (/ISO) P18911 (/ISO) P22605 (/ISO)
Dendrite GO:0030425
A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
3 A0A0G2JW78 (/IDA) P11416 (/IDA) Q499N1 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
3 A0A0G2JW78 (/IDA) P22448 (/IDA) Q499N1 (/IDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
2 P22448 (/IDA) Q90966 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 P18911 (/ISO) P22605 (/ISO)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
2 A0A0G2JW78 (/IDA) Q499N1 (/IDA)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
1 P10276 (/IDA)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
1 P11416 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P13631 (/ISS)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
1 P18911 (/IDA)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
1 P13631 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P11416 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P11416 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P10276 (/IC)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
1 P11416 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P13631 (/NAS)
Death-inducing signaling complex GO:0031264
A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10.
1 Q15156 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 P11416 (/IDA)