The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"ATP-grasp fold, B domain
".
FunFam 30857: Succinyl-CoA ligase subunit beta
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Succinate-CoA ligase (GDP-forming) activity GO:0004776
Catalysis of the reaction: GTP + succinate + CoA = GDP + succinyl-CoA + phosphate.
|
3 | B1H270 (/IDA) F1LPV8 (/IDA) Q68FT4 (/IDA) |
|
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
|
3 | B1H270 (/IDA) F1LPV8 (/IDA) Q68FT4 (/IDA) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
3 | B1H270 (/IDA) F1LPV8 (/IDA) Q68FT4 (/IDA) |
|
Succinate-CoA ligase (GDP-forming) activity GO:0004776
Catalysis of the reaction: GTP + succinate + CoA = GDP + succinyl-CoA + phosphate.
|
1 | Q96I99 (/NAS) |
|
Succinate-semialdehyde dehydrogenase (NAD+) activity GO:0004777
Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.
|
1 | Q9Z2I8 (/ISA) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
|
3 | B1H270 (/IDA) F1LPV8 (/IDA) Q68FT4 (/IDA) |
|
Succinyl-CoA metabolic process GO:0006104
The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A.
|
3 | B1H270 (/IDA) F1LPV8 (/IDA) Q68FT4 (/IDA) |
|
Succinate metabolic process GO:0006105
The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.
|
3 | B1H270 (/IDA) F1LPV8 (/IDA) Q68FT4 (/IDA) |
|
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
|
1 | Q96I99 (/TAS) |
|
Succinyl-CoA metabolic process GO:0006104
The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A.
|
1 | Q96I99 (/NAS) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
6 | A0A024R325 (/IDA) B1H270 (/IDA) F1LPV8 (/IDA) Q68FT4 (/IDA) Q96I99 (/IDA) Q9Z2I8 (/IDA) |
|
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
|
3 | B1H270 (/IDA) F1LPV8 (/IDA) Q68FT4 (/IDA) |
|
Succinate-CoA ligase complex (GDP-forming) GO:0045244
A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP.
|
3 | B1H270 (/IDA) F1LPV8 (/IDA) Q68FT4 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q55AI5 (/ISS) Q869S7 (/ISS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | A0A024R325 (/IDA) Q96I99 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q9Z2I8 (/ISO) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
1 | Q96I99 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9Z2I8 (/ISO) |
