The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 16759: D-lactate dehydrogenase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
D-lactate dehydrogenase. [EC: 1.1.1.28]
(R)-lactate + NAD(+) = pyruvate + NADH.
    2730 A0A009H4U2 A0A009H4U2 A0A009IR12 A0A009IR12 A0A009JMP6 A0A009JMP6 A0A009LKB4 A0A009LKB4 A0A009QQY9 A0A009QQY9
    (2720 more...)
    D-lactate dehydrogenase (cytochrome c-553). [EC: 1.1.2.5]
    (R)-lactate + 2 ferricytochrome c-553 = pyruvate + 2 ferrocytochrome c-553 + 2 H(+).
    • The enzyme from the sulfate-reducing bacterium Desulfovibrio vulgaris can also act on (R)-2-hydroxybutanoate.
    14 A0A0H5QFQ3 A0A0H5QFQ3 A0A1L9ETR7 A0A1L9ETR7 K8B7Y9 K8B7Y9 W1EQY3 W1EQY3 W1F4Y6 W1F4Y6
    (4 more...)
    UDP-N-acetylmuramate dehydrogenase. [EC: 1.3.1.98]
    UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.
    • NADH can to a lesser extent replace NADPH.
    • Formerly EC 1.1.1.158.
    2 A0A1L9ETR7 A0A1L9ETR7
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