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CATH Superfamily 3.30.460.10

Beta Polymerase, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Beta Polymerase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8552: Highly thermostable kanamycin nucleotidyltransfera...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Gentamicin 2''-nucleotidyltransferase. [EC: 2.7.7.46]
Nucleoside triphosphate + gentamicin = diphosphate + 2''-nucleotidylgentamicin.
  • ATP, dATP, CTP, ITP and GTP can act as donors.
  • Kanamycin, tobramycin and sisomicin can also act as acceptors.
  • The nucleotidyl residue is transferred to the 2-hydroxy group of the 3-amino-3-deoxy-D-glucose moiety in the antibiotic.
 62 A0A0F5X6K1 A0A0F5X6K1 A0A0H3JNV2 A0A0H3JNV2 A0A0H3JS65 A0A0H3JS65 A0A0U2NJU6 A0A0U2NJU6 A0A0W3ATB9 A0A0W3ATB9
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