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CATH Superfamily 3.30.460.10

Beta Polymerase, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Beta Polymerase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 18087: Nuclear poly(A) polymerase 1

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Polynucleotide adenylyltransferase. [EC: 2.7.7.19]
ATP + RNA(n) = diphosphate + RNA(n+1).
  • Also acts slowly with CTP.
  • Catalyzes template-independent extension of the 3'-end of a DNA strand by one nucleotide at a time.
  • Cannot initiate a chain de novo.
  • The primer, depending on the source of the enzyme, may be an RNA or DNA fragment or oligo(A) bearing a 3'-OH terminal group.
  • See also EC 2.7.7.6.
 95 A0A024R6M3 A0A024VBL8 A0A024VJ52 A0A024WAD2 A0A024WUL1 A0A024XCS2 A0A060T7P5 A0A061I5I5 A0A061IL84 A0A074T6X9
(85 more...)
DNA (cytosine-5-)-methyltransferase. [EC: 2.1.1.37]
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
  • See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
  • Formerly EC 2.1.1.73.
 1 A0A0F7S996
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