The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Beta Polymerase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17821: GTP pyrophosphokinase (P)ppGpp synthetase I

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
GTP diphosphokinase. [EC: 2.7.6.5]
ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.
  • GDP can also act as acceptor.
1457 A0A011MK94 A0A017IA95 A0A022PH13 A0A023NUA0 A0A023V211 A0A023Y062 A0A023Z1S0 A0A024KPD3 A0A025CVY8 A0A026S385
(1447 more...)
Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase. [EC: 3.1.7.2]
Guanosine 3',5'-bis(diphosphate) + H(2)O = guanosine 5'-diphosphate + diphosphate.
    210 A0A023Z1S0 A0A024KPD3 A0A025CVY8 A0A026S385 A0A026V984 A0A027U842 A0A028A6R2 A0A028ECI5 A0A029HL92 A0A029IL26
    (200 more...)
    Histidine kinase. [EC: 2.7.13.3]
    ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
    • This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine).
    • A number of histones can act as acceptor.
    1 A8T9A3
    Threonine--tRNA ligase. [EC: 6.1.1.3]
    ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).
      1 A0A068R953
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