The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 87707: Aryl hydrocarbon receptor repressor
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Core promoter sequence-specific DNA binding GO:0001046
Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter region composed of the transcription start site and binding sites for the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.
|
19 |
A0A087QWY7 (/ISS)
A0A091F9I0 (/ISS)
A0A091FM79 (/ISS)
A0A091JIQ5 (/ISS)
A0A091KUF4 (/ISS)
A0A091NYV0 (/ISS)
A0A091VLH0 (/ISS)
A0A091WLL3 (/ISS)
A0A093BMQ1 (/ISS)
A0A093C9U5 (/ISS)
(9 more) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
19 |
A0A087QWY7 (/ISS)
A0A091F9I0 (/ISS)
A0A091FM79 (/ISS)
A0A091JIQ5 (/ISS)
A0A091KUF4 (/ISS)
A0A091NYV0 (/ISS)
A0A091VLH0 (/ISS)
A0A091WLL3 (/ISS)
A0A093BMQ1 (/ISS)
A0A093C9U5 (/ISS)
(9 more) |
|
Transcriptional repressor activity, RNA polymerase II transcription factor binding GO:0001191
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
|
3 | B0S7S2 (/IDA) Q3T2L2 (/IDA) Q3T2L3 (/IDA) |
|
Core promoter sequence-specific DNA binding GO:0001046
Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter region composed of the transcription start site and binding sites for the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.
|
1 | E5L8C8 (/IDA) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q3T2L3 (/IDA) |
|
BHLH transcription factor binding GO:0043425
Interacting selectively and non-covalently with any of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.
|
1 | E5L8C8 (/IPI) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
1 | E5L8C8 (/IDA) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
19 |
A0A087QWY7 (/ISS)
A0A091F9I0 (/ISS)
A0A091FM79 (/ISS)
A0A091JIQ5 (/ISS)
A0A091KUF4 (/ISS)
A0A091NYV0 (/ISS)
A0A091VLH0 (/ISS)
A0A091WLL3 (/ISS)
A0A093BMQ1 (/ISS)
A0A093C9U5 (/ISS)
(9 more) |
|
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | B0S7S2 (/IMP) Q3T2L2 (/IMP) Q3T2L3 (/IMP) |
|
Cellular response to xenobiotic stimulus GO:0071466
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
|
3 | B0S7S2 (/IDA) Q3T2L2 (/IDA) Q3T2L3 (/IDA) |
|
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
|
2 | A9YTQ3 (/TAS) Q3U1U7 (/TAS) |
|
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q3U1U7 (/IDA) |
|
Response to xenobiotic stimulus GO:0009410
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
|
1 | Q3U1U7 (/IC) |
|
Positive regulation of protein sumoylation GO:0033235
Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.
|
1 | Q3U1U7 (/IDA) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q3U1U7 (/IDA) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | E5L8C8 (/IMP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
19 |
A0A087QWY7 (/ISS)
A0A091F9I0 (/ISS)
A0A091FM79 (/ISS)
A0A091JIQ5 (/ISS)
A0A091KUF4 (/ISS)
A0A091NYV0 (/ISS)
A0A091VLH0 (/ISS)
A0A091WLL3 (/ISS)
A0A093BMQ1 (/ISS)
A0A093C9U5 (/ISS)
(9 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q3T2L3 (/IDA) Q3U1U7 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | A9YTQ3 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q3U1U7 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | A9YTQ3 (/TAS) |
|
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
1 | E5L8C8 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | A9YTQ3 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q3U1U7 (/ISO) |