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CATH Superfamily 3.30.43.10

Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5293: 6-hydroxy-D-nicotine oxidase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
(R)-6-hydroxynicotine oxidase. [EC: 1.5.3.6]
(R)-6-hydroxynicotine + H(2)O + O(2) = 1-(6-hydroxypyridin-3-yl)-4- (methylamino)butan-1-one + H(2)O(2).
  • The enzyme, which participates in nicotine degradation, is specific for (R) isomer of 6-hydroxynicotine, derived from the uncommon (R)- nicotine.
  • The bacterium Arthrobacter nicotinovorans, in which this enzyme was originally discovered, has a different enzyme that catalyzes a similar reaction with the (S)-isomer (cf. EC 1.5.3.5).
 6 P08159 P08159 Q79DW3 Q79DW3 Q8GAG1 Q8GAG1