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CATH Superfamily 3.30.43.10

Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12009: D-lactate dehydrogenase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
D-lactate dehydrogenase. [EC: 1.1.1.28]
(R)-lactate + NAD(+) = pyruvate + NADH.
    		 3686 A0A009GB62 A0A009GB62 A0A009H4U2 A0A009H4U2 A0A009H7V4 A0A009H7V4 A0A009IR12 A0A009IR12 A0A009JMP6 A0A009JMP6
    (3676 more...)
    D-lactate dehydrogenase (cytochrome c-553). [EC: 1.1.2.5]
    (R)-lactate + 2 ferricytochrome c-553 = pyruvate + 2 ferrocytochrome c-553 + 2 H(+).
    • The enzyme from the sulfate-reducing bacterium Desulfovibrio vulgaris can also act on (R)-2-hydroxybutanoate.
    		 46 A0A060Q8L6 A0A060Q8L6 A0A090P4V6 A0A090P4V6 A0A0A2BHD9 A0A0A2BHD9 A0A0A2BN63 A0A0A2BN63 A0A0H5QFQ3 A0A0H5QFQ3
    (36 more...)
    UDP-N-acetylmuramate dehydrogenase. [EC: 1.3.1.98]
    UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.
    • NADH can to a lesser extent replace NADPH.
    • Formerly EC 1.1.1.158.
    		 2 A0A1L9ETR7 A0A1L9ETR7