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CATH Superfamily 3.30.43.10

Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11883: Berberine bridge enzyme-like protein

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Cinnamyl-alcohol dehydrogenase. [EC: 1.1.1.195]
Cinnamyl alcohol + NADP(+) = cinnamaldehyde + NADPH.
  • Acts on coniferyl alcohol, sinapyl alcohol, 4-coumaryl alcohol and cinnamyl alcohol (cf. EC 1.1.1.194).
 6 A0A178VZ42 A0A178VZ42 O64743 O64743 Q93ZA3 Q93ZA3
Coniferyl-alcohol dehydrogenase. [EC: 1.1.1.194]
Coniferyl alcohol + NADP(+) = coniferyl aldehyde + NADPH.
  • Specific for coniferyl alcohol; does not act on cinnamyl alcohol, 4-coumaryl alcohol or sinapyl alcohol.
 6 A0A178VZ42 A0A178VZ42 O64743 O64743 Q93ZA3 Q93ZA3
Reticuline oxidase. [EC: 1.21.3.3]
(S)-reticuline + O(2) = (S)-scoulerine + H(2)O(2).
  • Acts on (S)-reticuline and related compounds, converting the N-methyl group into the methylene bridge ('berberine bridge') of (S)- tetrahydroprotoberberines.
  • The product of the reaction, (S)-scoulerine, is a precursor of protopine, protoberberine and benzophenanthridine alkaloid biosynthesis in plants.
  • Formerly EC 1.5.3.9.
 4 B9SB02 B9SB02 B9SB04 B9SB04