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CATH Superfamily 3.30.43.10

Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11771: Probable D-2-hydroxyglutarate dehydrogenase, mitoc...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
D-lactate dehydrogenase (cytochrome). [EC: 1.1.2.4]
(R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c + 2 H(+).
    		 17 A0A060T7G3 A0A0B2RUF4 A0A0B2SCA8 A0A0L8VSA6 A3LVT5 A6ZXF3 B3LH62 B9S687 B9WDR5 C7GL24
    (7 more...)
    D-2-hydroxyglutarate dehydrogenase. [EC: 1.1.99.39]
    (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.
    • The enzyme has no activity with NAD(+) or NADP(+), and was assayed in vitro using artificial electron acceptors.
    • It has lower activity with (R)-lactate, (R)-2-hydroxybutyrate and meso-tartrate, and no activity with the (S) isomers.
    		 3 B8B7X6 O23240 Q7XI14
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