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CATH Superfamily 3.30.420.40

ATPase, nucleotide binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 78391: Probable tRNA N6-adenosine threonylcarbamoyltransf...

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
N(6)-L-threonylcarbamoyladenine synthase. [EC: 2.3.1.234]
L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L- threonylcarbamoyladenine(37) in tRNA.
  • The enzyme is involved in the synthesis of N(6)- threonylcarbamoyladenosine(37) in tRNAs, which is found in tRNAs with the anticodon NNU, i.e. tRNA(Ile), tRNA(Thr), tRNA(Asn), tRNA(Lys), tRNA(Ser) and tRNA(Arg).
  • Formerly EC 2.6.99.4.
 616 A0A063Z6L5 A0A063Z6L5 A0A063ZJS2 A0A063ZJS2 A0A075WK86 A0A075WK86 A0A076LB51 A0A076LB51 A0A089ZA20 A0A089ZA20
(606 more...)
Non-specific serine/threonine protein kinase. [EC: 2.7.11.1]
ATP + a protein = ADP + a phosphoprotein.
  • This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.
  • Formerly EC 2.7.1.37 and EC 2.7.1.70.
 494 A0A063Z6L5 A0A063Z6L5 A0A063ZJS2 A0A063ZJS2 A0A075FV20 A0A075FV20 A0A075G206 A0A075G206 A0A075GGN3 A0A075GGN3
(484 more...)
O-sialoglycoprotein endopeptidase. [EC: 3.4.24.57]
Hydrolysis of O-sialoglycoproteins; cleaves 31-Arg-|-Asp-32 bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated.
  • Inhibited by EDTA (100 mM) and 1,10-phenanthroline.
  • Belongs to peptidase family M22.
 114 A0A075WK86 A0A075WK86 A0A088SFN1 A0A088SFN1 A0A0A1U2A1 A0A0A1U2A1 A0A0B2Q4T2 A0A0B2Q4T2 A0A0B2SDI2 A0A0B2SDI2
(104 more...)
DNA-directed DNA polymerase. [EC: 2.7.7.7]
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
  • Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.
  • Cannot initiate a chain de novo.
  • Requires a primer which may be DNA or RNA.
  • See also EC 2.7.7.49.
 10 A0A081RLY6 A0A081RLY6 A0A087RNS9 A0A087RNS9 A0A087RSA6 A0A087RSA6 A0A087RV91 A0A087RV91 A0A087S4G7 A0A087S4G7
Dihydrolipoyllysine-residue acetyltransferase. [EC: 2.3.1.12]
Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)- (S-acetyldihydrolipoyl)lysine.
  • A multimer (24-mer or 60-mer, depending on the source) of this enzyme forms the core of the pyruvate dehydrogenase multienzyme complex, and binds tightly both EC 1.2.4.1 and EC 1.8.1.4.
  • The lipoyl group of this enzyme is reductively acetylated by EC 1.2.4.1, and the only observed direction catalyzed by EC 2.3.1.12 is that where the acetyl group is passed to coenzyme A.
 2 A0A1J8PQN6 A0A1J8PQN6