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CATH Superfamily 3.30.420.10

Ribonuclease H-like superfamily/Ribonuclease H

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Ribonuclease H-like superfamily/Ribonuclease H
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 18494: 3'-5' exonuclease family protein, ribonuclease D

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Ribonuclease D. [EC: 3.1.13.5]
Exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.
  • Alteration of the 3'-terminal base has no effect on the rate of hydrolysis whereas modification of the 3'-terminal sugar has a major effect.
  • tRNA terminating with a 3'-phosphate is completely inactive.
  • This enzyme can convert a tRNA precursor into a mature tRNA.
 20 A0A045IH64 A0A0G4E1M0 A0A0H3LJE1 A0A0H3M998 A0A0H3P4W7 A0A0K2KV80 A0A0T9AVM2 A0A0T9E5F0 A0A109SZ16 A0A1A9EA71
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