The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Zinc/RING finger domain, C3HC4 (zinc finger)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 61756: TNF-receptor-associated factor 4, isoform E

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 A8DYU9 (/IPI) Q9UAC5 (/IPI) Q9XYR0 (/IPI)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
3 A8DYU9 (/IMP) Q9UAC5 (/IMP) Q9XYR0 (/IMP)
Apical constriction involved in gastrulation GO:0003384
The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation.
3 A8DYU9 (/IMP) Q9UAC5 (/IMP) Q9XYR0 (/IMP)
Phagocytosis GO:0006909
An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
3 A8DYU9 (/IMP) Q9UAC5 (/IMP) Q9XYR0 (/IMP)
Ventral furrow formation GO:0007370
Formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.
3 A8DYU9 (/IMP) Q9UAC5 (/IMP) Q9XYR0 (/IMP)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
3 A8DYU9 (/TAS) Q9UAC5 (/TAS) Q9XYR0 (/TAS)
Adherens junction organization GO:0034332
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
3 A8DYU9 (/IMP) Q9UAC5 (/IMP) Q9XYR0 (/IMP)
Salivary gland cell autophagic cell death GO:0035071
The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis.
3 A8DYU9 (/IEP) Q9UAC5 (/IEP) Q9XYR0 (/IEP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
3 A8DYU9 (/IMP) Q9UAC5 (/IMP) Q9XYR0 (/IMP)
Asymmetric protein localization involved in cell fate determination GO:0045167
Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.
3 A8DYU9 (/IMP) Q9UAC5 (/IMP) Q9XYR0 (/IMP)
Positive regulation of JNK cascade GO:0046330
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
3 A8DYU9 (/IGI) Q9UAC5 (/IGI) Q9XYR0 (/IGI)
Imaginal disc fusion, thorax closure GO:0046529
The joining of the parts of the wing imaginal discs, giving rise to the adult thorax.
3 A8DYU9 (/IGI) Q9UAC5 (/IGI) Q9XYR0 (/IGI)
Autophagic cell death GO:0048102
A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.
3 A8DYU9 (/IEP) Q9UAC5 (/IEP) Q9XYR0 (/IEP)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
3 A8DYU9 (/IMP) Q9UAC5 (/IMP) Q9XYR0 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 A8DYU9 (/IDA) Q9UAC5 (/IDA) Q9XYR0 (/IDA)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
3 A8DYU9 (/IDA) Q9UAC5 (/IDA) Q9XYR0 (/IDA)
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
3 A8DYU9 (/IDA) Q9UAC5 (/IDA) Q9XYR0 (/IDA)