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CATH Superfamily 3.30.40.10

Zinc/RING finger domain, C3HC4 (zinc finger)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Zinc/RING finger domain, C3HC4 (zinc finger)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 61513: Histone-lysine N-methyltransferase NSD3

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Histone-lysine N-methyltransferase. [EC: 2.1.1.43]
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
    		 367 A0A024TKZ5 A0A060WM68 A0A061IHJ2 A0A068W7A8 A0A068YCN5 A0A074ZJK2 A0A081AH40 A0A087QGP1 A0A087X2L3 A0A087XCX9
    (357 more...)
    DNA helicase. [EC: 3.6.4.12]
    ATP + H(2)O = ADP + phosphate.
    • DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA.
    • Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15).
    • Some helicases unwind DNA as well as RNA (4,9).
    • May be identical with EC 3.6.4.13 (RNA helicase).
    		 18 A0A0B2PE49 A0A0B2S733 A0A0B2SLA6 A0A0B2SWQ8 A0A1C3KU33 A0A1C3KU33 A0A1C3KZK4 A0A1D3SMQ9 A0A1D3SMQ9 A0A1D3TJC7
    (8 more...)
    Non-specific serine/threonine protein kinase. [EC: 2.7.11.1]
    ATP + a protein = ADP + a phosphoprotein.
    • This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.
    • Formerly EC 2.7.1.37 and EC 2.7.1.70.
    		 2 L0B0F0 L0B0F0
    Pectinesterase. [EC: 3.1.1.11]
    Pectin + n H(2)O = n methanol + pectate.
      		 1 A0A0B2NZ21
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