The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors.

Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.

Repression of transcription of ribosomal DNA by altering the structure of chromatin.

The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.

The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.

Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.

The cellular synthesis of RNA on a template of DNA.

Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.

Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

The modification of histones by removal of acetyl groups.

Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.

Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).

Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

Any process that activates or increases the frequency, rate or extent of viral transcription.

Repression of transcription of ribosomal DNA by altering the structure of chromatin.

Repression of transcription of ribosomal DNA by altering the structure of chromatin.

Repression of transcription of ribosomal DNA by altering the structure of chromatin.

The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.

Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.

The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.

Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.

Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.

Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.

Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.

The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure.

The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure.

Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter.

The modification of histones by removal of acetyl groups.

The modification of histones by removal of methyl groups.

Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.

The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.

Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.

The formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.

The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone.

The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone.

The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone.

The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone.

The process by which an organism or tissue maintains a population of male germ-line stem cells.

Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).

The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 9 of the histone.

The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.

Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

Any process that modulates the frequency, rate or extent of the JAK-STAT signaling pathway.

Any process that activates or increases the frequency, rate or extent of viral transcription.

The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone.

Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis.

Any process that results in the assembly of chromatin into heterochromatin and contributes to chromatin silencing.

Any process that results in the assembly of chromatin into heterochromatin and contributes to chromatin silencing.

The modification of histone H4 by the removal of one or more acetyl groups.

Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.

Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair.

That part of the nuclear content other than the chromosomes or the nucleolus.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

That part of the nuclear content other than the chromosomes or the nucleolus.

That part of the nuclear content other than the chromosomes or the nucleolus.

Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.

A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals) and an RSF1 homolog. It mediates nucleosome deposition and generates regularly spaced nucleosome arrays. In mammals, RSF is involved in regulation of transcription from RNA polymerase II promoters).

A region of heterochromatin located at the rDNA repeats in a chromosome.

Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.

A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.

An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals) and an RSF1 homolog. It mediates nucleosome deposition and generates regularly spaced nucleosome arrays. In mammals, RSF is involved in regulation of transcription from RNA polymerase II promoters).

A region of heterochromatin located at the rDNA repeats in a chromosome.

Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex.