The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Zinc/RING finger domain, C3HC4 (zinc finger)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 60137: E3 ubiquitin-protein ligase TRIM33

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
1 Q9UPN9 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9UPN9 (/IPI)
Co-SMAD binding GO:0070410
Interacting selectively and non-covalently with a common mediator SMAD signaling protein.
1 Q9UPN9 (/IPI)
Co-SMAD binding GO:0070410
Interacting selectively and non-covalently with a common mediator SMAD signaling protein.
1 Q99PP7 (/ISO)
Co-SMAD binding GO:0070410
Interacting selectively and non-covalently with a common mediator SMAD signaling protein.
1 Q99PP7 (/ISS)
R-SMAD binding GO:0070412
Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
1 Q9UPN9 (/IPI)
R-SMAD binding GO:0070412
Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
1 Q99PP7 (/ISO)
R-SMAD binding GO:0070412
Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
1 Q99PP7 (/ISS)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q9UPN9 (/TAS)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
1 Q9UPN9 (/IDA)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
1 Q99PP7 (/ISO)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
1 Q99PP7 (/ISS)
Regulation of transforming growth factor beta receptor signaling pathway GO:0017015
Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
1 Q9UPN9 (/IDA)
Regulation of transforming growth factor beta receptor signaling pathway GO:0017015
Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
1 Q99PP7 (/ISO)
Regulation of transforming growth factor beta receptor signaling pathway GO:0017015
Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
1 Q99PP7 (/ISS)
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
1 Q6E2N3 (/IGI)
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
1 Q6E2N3 (/IMP)
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
1 Q9UPN9 (/IDA)
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
1 Q99PP7 (/ISO)
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
1 Q99PP7 (/ISS)
Fin development GO:0033333
The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.
1 Q6E2N3 (/IMP)
Regulation of transcription elongation from RNA polymerase II promoter GO:0034243
Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
1 Q6E2N3 (/IGI)
Embryonic hemopoiesis GO:0035162
The stages of blood cell formation that take place within the embryo.
1 Q6E2N3 (/IMP)
Post-embryonic hemopoiesis GO:0035166
The stages of blood cell formation that take place after completion of embryonic development.
1 Q6E2N3 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9UPN9 (/NAS)
Developmental pigmentation GO:0048066
The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.
1 Q6E2N3 (/IMP)
Primitive hemopoiesis GO:0060215
A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.
1 Q6E2N3 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q99PP7 (/IDA) Q9UPN9 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q99PP7 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9UPN9 (/TAS)