The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 59818: MYST histone acetyltransferase 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
|
2 | Q8BRB7 (/IDA) Q8WYB5 (/IDA) |
|
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
|
2 | Q8BRB7 (/ISS) Q8WML3 (/ISS) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
2 | Q8BRB7 (/ISS) Q8WML3 (/ISS) |
|
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
|
2 | Q8BRB7 (/ISS) Q8WML3 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q8WYB5 (/IPI) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
1 | Q8WYB5 (/IDA) |
|
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
|
1 | Q8WYB5 (/IDA) |
|
Protein complex binding GO:0032403
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | M0R4T9 (/IPI) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
|
2 | Q8BRB7 (/IDA) Q8WYB5 (/IDA) |
|
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
|
2 | Q8BRB7 (/ISS) Q8WML3 (/ISS) |
|
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
|
2 | Q8BRB7 (/ISS) Q8WML3 (/ISS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q8BRB7 (/ISS) Q8WML3 (/ISS) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q8BRB7 (/ISS) Q8WML3 (/ISS) |
|
Nucleosome assembly GO:0006334
The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
|
1 | Q8WYB5 (/NAS) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q8WYB5 (/NAS) |
|
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
|
1 | Q8WYB5 (/IDA) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q8WYB5 (/IDA) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q8WYB5 (/IDA) |
|
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | M0R4T9 (/IDA) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MOZ/MORF histone acetyltransferase complex GO:0070776
A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.
|
2 | Q8BRB7 (/ISS) Q8WML3 (/ISS) |
|
Nucleosome GO:0000786
A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
|
1 | Q8WYB5 (/NAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | M0R4T9 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q8WYB5 (/TAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q8WYB5 (/TAS) |
|
MOZ/MORF histone acetyltransferase complex GO:0070776
A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.
|
1 | Q8WYB5 (/IDA) |
