The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Zinc/RING finger domain, C3HC4 (zinc finger)
".
FunFam 59673: E3 ubiquitin-protein ligase DTX1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q61010 (/IPI) Q86UW9 (/IPI) Q86Y01 (/IPI) Q8R3P2 (/IPI) |
|
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
|
1 | Q86Y01 (/TAS) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
1 | Q9Y2E6 (/TAS) |
|
Notch binding GO:0005112
Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor.
|
1 | Q86Y01 (/IDA) |
|
Notch binding GO:0005112
Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor.
|
1 | Q61010 (/ISO) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | Q86Y01 (/IPI) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | Q61010 (/ISO) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
3 | Q61010 (/TAS) Q86Y01 (/TAS) Q8R3P2 (/TAS) |
|
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | Q61010 (/IDA) Q8R3P2 (/IDA) |
|
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
1 | Q86Y01 (/NAS) |
|
Transcription from RNA polymerase II promoter GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
|
1 | Q86Y01 (/TAS) |
|
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q86Y01 (/TAS) |
|
Notch signaling pathway GO:0007219
A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q61010 (/IMP) |
|
Regulation of Notch signaling pathway GO:0008593
Any process that modulates the frequency, rate or extent of the Notch signaling pathway.
|
1 | Q86Y01 (/IGI) |
|
Regulation of Notch signaling pathway GO:0008593
Any process that modulates the frequency, rate or extent of the Notch signaling pathway.
|
1 | Q61010 (/ISO) |
|
Glial cell differentiation GO:0010001
The process in which a relatively unspecialized cell acquires the specialized features of a glial cell.
|
1 | Q61010 (/IMP) |
|
Regulation of type I interferon production GO:0032479
Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
|
1 | Q9Y2E6 (/TAS) |
|
Negative regulation of T cell differentiation GO:0045581
Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation.
|
1 | Q61010 (/IDA) |
|
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
|
1 | Q86Y01 (/IGI) |
|
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
|
1 | Q61010 (/ISO) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | E7ET89 (/IDA) Q86UW9 (/IDA) Q86Y01 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | Q61010 (/TAS) Q86Y01 (/TAS) Q9Y2E6 (/TAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q61010 (/ISO) Q8R3P2 (/ISO) |
|
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
2 | E7ET89 (/IDA) Q86UW9 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q86Y01 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q86Y01 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q61010 (/ISO) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
1 | Q86Y01 (/IDA) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
1 | Q61010 (/ISO) |
|
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
1 | Q8R3P2 (/ISO) |
