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CATH Superfamily 3.30.390.30

FAD/NAD-linked reductase, C-terminal dimerisation domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3305: NADPH-dependent mycothiol reductase MTR

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutathione-disulfide reductase. [EC: 1.8.1.7]
2 glutathione + NADP(+) = glutathione disulfide + NADPH.
  • Activity is dependent on a redox-active disulfide in each of the active centers.
  • Formerly EC 1.6.4.2.
 15 A0A045HDF1 A0A083VZ54 A0A0G4E204 A0A0H3LCW2 A0A0H3M857 A0A0H3P8Q2 A0A0K2HZG3 A0A109SZE3 A5U6K7 F8M481
(5 more...)
Mycothione reductase. [EC: 1.8.1.15]
2 mycothiol + NAD(P)(+) = mycothione + NAD(P)H.
  • No activity with glutathione, trypanothione or coenzyme A as substrate.
 14 A0A045HDF1 A0A083VZ54 A0A0G4E204 A0A0H3LCW2 A0A0H3M857 A0A0H3P8Q2 A0A0K2HZG3 A0A109SZE3 A5U6K7 F8M481
(4 more...)