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CATH Superfamily 3.30.360.10

Dihydrodipicolinate Reductase; domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Dihydrodipicolinate Reductase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 23518: Succinyl-CoA reductase (NADPH)

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Malonyl CoA reductase (malonate semialdehyde-forming). [EC: 1.2.1.75]
Malonate semialdehyde + CoA + NADP(+) = malonyl-CoA + NADPH.
  • Catalyzes the reduction of malonyl-CoA to malonate semialdehyde, a key step in the 3-hydroxypropanoate and the 3-hydroxypropanoate/4-hydroxybutyrate cycles, autotrophic CO(2) fixation pathways found in some green non-sulfur phototrophic bacteria and some thermoacidophilic archaea, respectively.
  • The enzyme from Sulfolobus tokodaii has been purified, and found to contain one RNA molecule per two subunits.
  • The enzyme from Chloroflexus aurantiacus is bifunctional, and also catalyzes the next reaction in the pathway, EC 1.1.1.298.
 3 A0A088E3J5 A4YEN2 Q96YK1