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CATH Superfamily 3.30.342.10

DNA Polymerase, chain B, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
DNA Polymerase, chain B, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1148: DNA polymerase catalytic subunit

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
DNA-directed DNA polymerase. [EC: 2.7.7.7]
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
  • Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.
  • Cannot initiate a chain de novo.
  • Requires a primer which may be DNA or RNA.
  • See also EC 2.7.7.49.
 309 A0A059WP17 A0A060Q0V6 A0A076NAC6 A0A089WZ01 A0A097HY12 A0A0A7D8N5 A0A0A7D8T9 A0A0A7D9J4 A0A0A7DA09 A0A0B5E487
(299 more...)
Ribonuclease H. [EC: 3.1.26.4]
Endonucleolytic cleavage to 5'-phosphomonoester.
  • Acts on RNA-DNA hybrids.
 17 A0A0E3DA22 E1B1W8 P04292 P04293 P07917 P07918 P09252 P09854 P28858 P89453
(7 more...)