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CATH Superfamily 3.30.310.80

Kinase associated domain 1, KA1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Kinase associated domain 1, KA1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1160: MAP/microtubule affinity-regulating kinase 3

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Non-specific serine/threonine protein kinase. [EC: 2.7.11.1]
ATP + a protein = ADP + a phosphoprotein.
  • This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.
  • Formerly EC 2.7.1.37 and EC 2.7.1.70.
 714 A0A024R5B2 A0A026WQX3 A0A034VK46 A0A034VME3 A0A034VMG6 A0A034VQ15 A0A060W9G9 A0A060W9Y7 A0A061I034 A0A061I2J3
(704 more...)
[Tau protein] kinase. [EC: 2.7.11.26]
ATP + [tau protein] = ADP + [tau protein] phosphate.
  • Activated by tubulin.
  • Involved in the formation of paired helical filaments, which are the main fibrous component of all fibrillary lesions in brain and are associated with Alzheimer's disease.
  • Formerly EC 2.7.1.135.
 6 O08678 O08679 Q05512 Q7KZI7 Q8VHJ5 Q9P0L2