The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Imidazole glycerol phosphate dehydratase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1388: Histidine biosynthesis bifunctional protein HisB

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Imidazoleglycerol-phosphate dehydratase. [EC: 4.2.1.19]
D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2- oxopropyl phosphate + H(2)O.
    120 A0A015S2L5 A0A015T238 A0A015TFH2 A0A015TZH6 A0A015UL35 A0A015V8T7 A0A015VBM9 A0A015X7V9 A0A015Y7F3 A0A016A8P2
    (110 more...)
    Histidinol-phosphatase. [EC: 3.1.3.15]
    L-histidinol phosphate + H(2)O = L-histidinol + phosphate.
      120 A0A015S2L5 A0A015T238 A0A015TFH2 A0A015TZH6 A0A015UL35 A0A015V8T7 A0A015VBM9 A0A015X7V9 A0A015Y7F3 A0A016A8P2
      (110 more...)