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CATH Superfamily 3.30.230.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 28511: Diphosphomevalonate decarboxylase (AFU_orthologue ...

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Diphosphomevalonate decarboxylase. [EC: 4.1.1.33]
ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO(2).
    		 2856 A0A010QYS5 A0A010QYS5 A0A011RP07 A0A011RP07 A0A015LM53 A0A015LM53 A0A016UCG6 A0A016UCG6 A0A017SLT9 A0A017SLT9
    (2846 more...)
    Isopentenyl-diphosphate Delta-isomerase. [EC: 5.3.3.2]
    Isopentenyl diphosphate = dimethylallyl diphosphate.
      		 10 A0A0A8E8J7 A0A0A8E8J7 A0A0H4UT06 A0A0H4UT06 A0A0S7XYU3 A0A0S7XYU3 A9KC28 A9KC28 Q83DT5 Q83DT5
      Homoserine kinase. [EC: 2.7.1.39]
      ATP + L-homoserine = ADP + O-phospho-L-homoserine.
        		 4 A0A1E7XAE1 A0A1E7XAE1 A0A1L6Q5G6 A0A1L6Q5G6
        Pantoate kinase. [EC: 2.7.1.169]
        ATP + (R)-pantoate = ADP + (R)-4-phosphopantoate.
        • The conversion of (R)-pantoate to (R)-4'-phosphopantothenate is part of the pathway leading to biosynthesis of 4'-phosphopantetheine, an essential cofactor of coenzyme A and acyl-carrier protein.
        • In bacteria and eukaryotes this conversion is performed by condensation with beta-alanine, followed by phosphorylation (EC 6.3.2.1 and EC 2.7.1.33, respectively).
        • In archaea the order of these two steps is reversed, and phosphorylation precedes condensation with beta-alanine.
        		 2 Q58379 Q58379
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