The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

Phosphorylase Kinase; domain 1

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 64459: Casein kinase II subunit alpha

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Non-specific serine/threonine protein kinase. [EC:]
ATP + a protein = ADP + a phosphoprotein.
  • This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.
  • Formerly EC and EC
140 A0A087R8Q2 A0A087R8Q2 A0A091EU85 A0A091EU85 A0A091G8J4 A0A091G8J4 A0A091JEJ8 A0A091JEJ8 A0A091MCM8 A0A091MCM8
(130 more...)
[RNA-polymerase]-subunit kinase. [EC:]
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.
  • Appears to be distinct from other protein phosphokinases.
  • Brings about multiple phosphorylation of the unique C-terminal repeat domain of the largest subunit of eukaryotic EC
  • Does not phosphorylate casein, phosvitin or histone.
  • Formerly EC
6 B7PVH2 B7PVH2 E0VRT5 E0VRT5 L0B133 L0B133