The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Phosphorylase Kinase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 64164: G protein-coupled receptor kinase 4

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Rhodopsin kinase. [EC: 2.7.11.14]
ATP + [rhodopsin] = ADP + [rhodopsin] phosphate.
  • Acts on the bleached or activated form of rhodopsin.
  • Also phosphorylates the beta-adrenergic receptor, but more slowly.
  • Does not act on casein, histones or phosphovitin.
  • Inhibited by Zn(2+) and digitonin (cf. EC 2.7.11.15 and EC 2.7.11.16).
  • Formerly EC 2.7.1.97 and EC 2.7.1.125.
86 A0A087YAS8 A0A087YAS8 A0A091EHR8 A0A091EHR8 A0A096P018 A0A096P018 A0A0D9RXU7 A0A0D9RXU7 A0A0P7UT13 A0A0P7UT13
(76 more...)
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