The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Phosphorylase Kinase; domain 1
".
FunFam 5241: Cyclin-dependent protein kinase PHO85
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
10 | M9PE01 (/IPI) P17157 (/IPI) Q00537 (/IPI) Q7KM03 (/IPI) Q7KM04 (/IPI) Q7KM05 (/IPI) Q7KM08 (/IPI) Q8MZ44 (/IPI) Q94888 (/IPI) Q9XTK9 (/IPI) |
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
|
9 | M9PE01 (/IMP) P17157 (/IMP) Q7KM03 (/IMP) Q7KM04 (/IMP) Q7KM05 (/IMP) Q7KM08 (/IMP) Q8MZ44 (/IMP) Q94888 (/IMP) Q9XTK9 (/IMP) |
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
8 | M9PE01 (/IDA) Q7KM03 (/IDA) Q7KM04 (/IDA) Q7KM05 (/IDA) Q7KM08 (/IDA) Q8MZ44 (/IDA) Q94888 (/IDA) Q9XTK9 (/IDA) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
8 | M9PE01 (/NAS) Q7KM03 (/NAS) Q7KM04 (/NAS) Q7KM05 (/NAS) Q7KM08 (/NAS) Q8MZ44 (/NAS) Q94888 (/NAS) Q9XTK9 (/NAS) |
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
|
8 | M9PE01 (/ISS) Q7KM03 (/ISS) Q7KM04 (/ISS) Q7KM05 (/ISS) Q7KM08 (/ISS) Q8MZ44 (/ISS) Q94888 (/ISS) Q9XTK9 (/ISS) |
Cyclin binding GO:0030332
Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.
|
8 | M9PE01 (/IMP) Q7KM03 (/IMP) Q7KM04 (/IMP) Q7KM05 (/IMP) Q7KM08 (/IMP) Q8MZ44 (/IMP) Q94888 (/IMP) Q9XTK9 (/IMP) |
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
1 | Q00537 (/TAS) |
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
|
1 | P17157 (/IDA) |
There are 27 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
9 | M9PE01 (/IDA) P17157 (/IDA) Q7KM03 (/IDA) Q7KM04 (/IDA) Q7KM05 (/IDA) Q7KM08 (/IDA) Q8MZ44 (/IDA) Q94888 (/IDA) Q9XTK9 (/IDA) |
Embryonic development via the syncytial blastoderm GO:0001700
The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.
|
8 | M9PE01 (/IMP) Q7KM03 (/IMP) Q7KM04 (/IMP) Q7KM05 (/IMP) Q7KM08 (/IMP) Q8MZ44 (/IMP) Q94888 (/IMP) Q9XTK9 (/IMP) |
Morphogenesis of an epithelium GO:0002009
The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
|
8 | M9PE01 (/IMP) Q7KM03 (/IMP) Q7KM04 (/IMP) Q7KM05 (/IMP) Q7KM08 (/IMP) Q8MZ44 (/IMP) Q94888 (/IMP) Q9XTK9 (/IMP) |
Instar larval development GO:0002168
The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster.
|
8 | M9PE01 (/IMP) Q7KM03 (/IMP) Q7KM04 (/IMP) Q7KM05 (/IMP) Q7KM08 (/IMP) Q8MZ44 (/IMP) Q94888 (/IMP) Q9XTK9 (/IMP) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
8 | M9PE01 (/IMP) Q7KM03 (/IMP) Q7KM04 (/IMP) Q7KM05 (/IMP) Q7KM08 (/IMP) Q8MZ44 (/IMP) Q94888 (/IMP) Q9XTK9 (/IMP) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
8 | M9PE01 (/ISS) Q7KM03 (/ISS) Q7KM04 (/ISS) Q7KM05 (/ISS) Q7KM08 (/ISS) Q8MZ44 (/ISS) Q94888 (/ISS) Q9XTK9 (/ISS) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
8 | M9PE01 (/NAS) Q7KM03 (/NAS) Q7KM04 (/NAS) Q7KM05 (/NAS) Q7KM08 (/NAS) Q8MZ44 (/NAS) Q94888 (/NAS) Q9XTK9 (/NAS) |
Metamorphosis GO:0007552
A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster.
|
8 | M9PE01 (/IMP) Q7KM03 (/IMP) Q7KM04 (/IMP) Q7KM05 (/IMP) Q7KM08 (/IMP) Q8MZ44 (/IMP) Q94888 (/IMP) Q9XTK9 (/IMP) |
Developmental growth GO:0048589
The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.
|
8 | M9PE01 (/IMP) Q7KM03 (/IMP) Q7KM04 (/IMP) Q7KM05 (/IMP) Q7KM08 (/IMP) Q8MZ44 (/IMP) Q94888 (/IMP) Q9XTK9 (/IMP) |
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
|
1 | P17157 (/IGI) |
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
|
1 | P17157 (/IMP) |
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P17157 (/IGI) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
1 | Q00537 (/TAS) |
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
1 | P17157 (/IGI) |
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
1 | P17157 (/IMP) |
Positive regulation of macroautophagy GO:0016239
Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.
|
1 | P17157 (/IMP) |
Negative regulation of macroautophagy GO:0016242
Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.
|
1 | P17157 (/IMP) |
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
1 | P17157 (/IGI) |
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
1 | P17157 (/IMP) |
Regulation of establishment or maintenance of cell polarity GO:0032878
Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
|
1 | P17157 (/IGI) |
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
|
1 | P17157 (/IDA) |
Negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
1 | P17157 (/IGI) |
Negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
1 | P17157 (/IMP) |
Negative regulation of glycogen biosynthetic process GO:0045719
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
|
1 | P17157 (/IMP) |
Negative regulation of phosphate metabolic process GO:0045936
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
|
1 | P17157 (/IGI) |
Negative regulation of calcium-mediated signaling GO:0050849
Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.
|
1 | P17157 (/IGI) |
Positive regulation of phospholipid biosynthetic process GO:0071073
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
|
1 | P17157 (/IDA) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
8 | M9PE01 (/IDA) Q7KM03 (/IDA) Q7KM04 (/IDA) Q7KM05 (/IDA) Q7KM08 (/IDA) Q8MZ44 (/IDA) Q94888 (/IDA) Q9XTK9 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
8 | M9PE01 (/IDA) Q7KM03 (/IDA) Q7KM04 (/IDA) Q7KM05 (/IDA) Q7KM08 (/IDA) Q8MZ44 (/IDA) Q94888 (/IDA) Q9XTK9 (/IDA) |
Cyclin-dependent protein kinase holoenzyme complex GO:0000307
Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.
|
1 | P17157 (/IPI) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P17157 (/IDA) |
Pho85-Pho80 CDK-cyclin complex GO:1990860
A cyclin dependent kinase (CDK) complex that contains a kinase subunit and a regulatory cyclin subunit. An example of this complex in budding yeast S. cerevisiae consists of the Pho85 kinase and the Pho80 cyclin.
|
1 | P17157 (/IDA) |