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CATH Superfamily 3.30.200.20

Phosphorylase Kinase; domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Phosphorylase Kinase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3751: Insulin-like growth factor 1 receptor

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Receptor protein-tyrosine kinase. [EC: 2.7.10.1]
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
  • The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans.
  • In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies.
  • Formerly EC 2.7.1.112.
 163 A0A067RC78 A0A068F0Z0 A0A084WIB4 A0A085M3M3 A0A085NFW6 A0A0A9XLS6 A0A0B1STN0 A0A0B4KZW6 A0A0B7A3E7 A0A0C4UQW2
(153 more...)
Guanylate cyclase. [EC: 4.6.1.2]
GTP = 3',5'-cyclic GMP + diphosphate.
  • Also acts on ITP and dGTP.
 7 A0A164NKR9 A0A1I8N5J4 C4XV88 H9J2R3 R7US23 T1PJT0 W4XHH0
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