View in Gene3D

CATH Superfamily 3.30.1740.10

Zinc finger, PARP-type

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Zinc finger, PARP-type
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 420: Poly [ADP-ribose] polymerase 1

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
NAD(+) ADP-ribosyltransferase. [EC: 2.4.2.30]
NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D- ribosyl)(n+1)-acceptor.
  • The ADP-D-ribosyl group of NAD(+) is transferred to an acceptor carboxy group on a histone or the enzyme itself, and further ADP- ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units.
 102 A0A024R3T8 A0A060XA31 A0A087XA08 A0A091CQW4 A0A0A7HSK2 A0A0B8RZA8 A0A0F7Z5V8 A0A0F8BFG1 A0A0Q3QQT1 A0A0S7KTM7
(92 more...)
CATH-Gene3D is a Global Biodata Core Resource Learn more...