The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Methylated DNA-protein cysteine methyltransferase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 101: ADA regulatory protein / Methylated-DNA--protein-c...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Methylated-DNA--[protein]-cysteine S-methyltransferase. [EC: 2.1.1.63]
DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine.
  • This protein is involved in the repair of alkylated DNA.
  • It acts only on the alkylated DNA (cf. EC 3.2.2.20 and EC 3.2.2.21).
  • This enzyme catalyzes only one turnover and therefore is not strictly catalytic.
24 A0A0F6B3Z5 A0A0F7JBG5 A0A0G2NPL7 A0A0H3BQX8 A0A0H3NF59 A0A0M2IWF6 A0A0N1TUW5 A0A0T9VP50 A0A0W4IHQ7 A0A1C0ZN14
(14 more...)