The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Classic Zinc Finger
".
FunFam 23075: Zinc finger protein ZFPM1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O35615 (/IPI) Q8IX07 (/IPI) |
|
RNA polymerase II core promoter sequence-specific DNA binding GO:0000979
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase II basal transcription machinery.
|
1 | O35615 (/IDA) |
|
Transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001078
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q8IX07 (/IDA) |
|
Transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001078
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O35615 (/ISO) |
|
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
|
1 | Q8IX07 (/IPI) |
|
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
|
1 | O35615 (/ISO) |
|
RNA polymerase II activating transcription factor binding GO:0001102
Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.
|
1 | O35615 (/IDA) |
|
Transcription corepressor activity GO:0003714
Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
|
1 | O35615 (/TAS) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
1 | Q8IX07 (/IPI) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
1 | O35615 (/ISO) |
There are 52 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O35615 (/IDA) |
|
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O35615 (/IMP) |
|
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O35615 (/TAS) |
|
T-helper cell lineage commitment GO:0002295
The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes.
|
1 | Q8IX07 (/IC) |
|
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
|
1 | O35615 (/IMP) |
|
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
|
1 | Q8IX07 (/ISS) |
|
Atrioventricular valve morphogenesis GO:0003181
The process in which the structure of the atrioventricular valve is generated and organized.
|
1 | O35615 (/IMP) |
|
Atrioventricular valve morphogenesis GO:0003181
The process in which the structure of the atrioventricular valve is generated and organized.
|
1 | Q8IX07 (/ISS) |
|
Mitral valve formation GO:0003192
The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
|
1 | O35615 (/IMP) |
|
Mitral valve formation GO:0003192
The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
|
1 | Q8IX07 (/ISS) |
|
Tricuspid valve formation GO:0003195
The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
|
1 | O35615 (/IMP) |
|
Tricuspid valve formation GO:0003195
The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
|
1 | Q8IX07 (/ISS) |
|
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | O35615 (/IMP) |
|
Blood coagulation GO:0007596
The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
|
1 | Q8IX07 (/TAS) |
|
Regulation of definitive erythrocyte differentiation GO:0010724
Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis.
|
1 | Q8IX07 (/IDA) |
|
Regulation of definitive erythrocyte differentiation GO:0010724
Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis.
|
1 | Q8IX07 (/IMP) |
|
Regulation of definitive erythrocyte differentiation GO:0010724
Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis.
|
1 | O35615 (/ISO) |
|
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
|
1 | O35615 (/IGI) |
|
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
|
1 | O35615 (/IMP) |
|
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
|
1 | Q8IX07 (/ISS) |
|
Megakaryocyte differentiation GO:0030219
The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte.
|
1 | O35615 (/IGI) |
|
Megakaryocyte differentiation GO:0030219
The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte.
|
1 | O35615 (/IMP) |
|
Megakaryocyte differentiation GO:0030219
The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte.
|
1 | Q8IX07 (/ISS) |
|
Platelet formation GO:0030220
The process in which platelets bud from long processes extended by megakaryocytes.
|
1 | Q8IX07 (/IGI) |
|
Platelet formation GO:0030220
The process in which platelets bud from long processes extended by megakaryocytes.
|
1 | O35615 (/ISO) |
|
Granulocyte differentiation GO:0030851
The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
|
1 | O35615 (/IMP) |
|
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
|
1 | O35615 (/IDA) |
|
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
|
1 | Q8IX07 (/ISS) |
|
Regulation of chemokine production GO:0032642
Any process that modulates the frequency, rate, or extent of chemokine production.
|
1 | O35615 (/IMP) |
|
Embryonic hemopoiesis GO:0035162
The stages of blood cell formation that take place within the embryo.
|
1 | O35615 (/IMP) |
|
Embryonic hemopoiesis GO:0035162
The stages of blood cell formation that take place within the embryo.
|
1 | Q8IX07 (/ISS) |
|
Megakaryocyte development GO:0035855
The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow.
|
1 | O35615 (/IMP) |
|
Positive regulation of interferon-gamma biosynthetic process GO:0045078
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma.
|
1 | Q8IX07 (/IDA) |
|
Positive regulation of interferon-gamma biosynthetic process GO:0045078
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma.
|
1 | O35615 (/ISO) |
|
Negative regulation of interleukin-4 biosynthetic process GO:0045403
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-4.
|
1 | Q8IX07 (/IDA) |
|
Negative regulation of interleukin-4 biosynthetic process GO:0045403
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-4.
|
1 | O35615 (/ISO) |
|
Negative regulation of fat cell differentiation GO:0045599
Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.
|
1 | O35615 (/IMP) |
|
Negative regulation of fat cell differentiation GO:0045599
Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.
|
1 | Q8IX07 (/ISS) |
|
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O35615 (/IDA) |
|
Homeostasis of number of cells GO:0048872
Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.
|
1 | O35615 (/IMP) |
|
Cardiac muscle tissue morphogenesis GO:0055008
The process in which the anatomical structures of cardiac muscle tissue are generated and organized.
|
1 | O35615 (/IMP) |
|
Cardiac muscle tissue morphogenesis GO:0055008
The process in which the anatomical structures of cardiac muscle tissue are generated and organized.
|
1 | Q8IX07 (/ISS) |
|
Definitive erythrocyte differentiation GO:0060318
Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis.
|
1 | O35615 (/IMP) |
|
Primitive erythrocyte differentiation GO:0060319
Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis.
|
1 | O35615 (/IMP) |
|
Negative regulation of mast cell differentiation GO:0060377
Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
|
1 | O35615 (/IDA) |
|
Negative regulation of mast cell differentiation GO:0060377
Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
|
1 | Q8IX07 (/ISS) |
|
Ventricular septum morphogenesis GO:0060412
The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.
|
1 | O35615 (/IMP) |
|
Ventricular septum morphogenesis GO:0060412
The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.
|
1 | Q8IX07 (/ISS) |
|
Atrial septum morphogenesis GO:0060413
The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.
|
1 | O35615 (/IMP) |
|
Atrial septum morphogenesis GO:0060413
The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.
|
1 | Q8IX07 (/ISS) |
|
Transcriptional activation by promoter-enhancer looping GO:0071733
The formation and maintenance of DNA loops that juxtapose the promoter and enhancer regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter.
|
1 | O35615 (/IDA) |
|
Transcriptional activation by promoter-enhancer looping GO:0071733
The formation and maintenance of DNA loops that juxtapose the promoter and enhancer regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter.
|
1 | Q8IX07 (/ISS) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O35615 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q8IX07 (/TAS) |
|
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
1 | Q8IX07 (/IDA) |
|
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
1 | O35615 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | O35615 (/IDA) |
|
Transcriptional repressor complex GO:0017053
A protein complex that possesses activity that prevents or downregulates transcription.
|
1 | Q8IX07 (/IDA) |
|
Transcriptional repressor complex GO:0017053
A protein complex that possesses activity that prevents or downregulates transcription.
|
1 | O35615 (/ISO) |