CATH Superfamily 3.30.160.20
The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 4246: Interferon-inducible double-stranded RNA-dependent...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O75569 (/IPI) Q9WTX2 (/IPI) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | O75569 (/IDA) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q9WTX2 (/ISO) |
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
|
1 | O75569 (/IDA) |
Double-stranded RNA binding GO:0003725
Interacting selectively and non-covalently with double-stranded RNA.
|
1 | Q9WTX2 (/ISO) |
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
|
1 | O75569 (/TAS) |
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | O75569 (/IPI) |
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q9WTX2 (/ISO) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q4V8C7 (/IPI) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | O75569 (/IPI) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q9WTX2 (/ISO) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | O75569 (/IPI) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9WTX2 (/ISO) |
There are 25 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Production of siRNA involved in RNA interference GO:0030422
Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.
|
3 | Q2HJ92 (/ISS) Q4V8C7 (/ISS) Q9WTX2 (/ISS) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
1 | Q9WTX2 (/IDA) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
1 | Q2HJ92 (/ISS) |
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
|
1 | O75569 (/TAS) |
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | Q4V8C7 (/IMP) |
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | O75569 (/TAS) |
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
|
1 | O75569 (/TAS) |
MiRNA metabolic process GO:0010586
The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
|
1 | O75569 (/TAS) |
Production of siRNA involved in RNA interference GO:0030422
Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.
|
1 | O75569 (/IDA) |
Production of siRNA involved in RNA interference GO:0030422
Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.
|
1 | Q9WTX2 (/ISO) |
Production of siRNA involved in RNA interference GO:0030422
Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.
|
1 | O75569 (/TAS) |
Pre-miRNA processing GO:0031054
Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule.
|
1 | O75569 (/IDA) |
Pre-miRNA processing GO:0031054
Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule.
|
1 | Q9WTX2 (/ISO) |
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
1 | Q9WTX2 (/IDA) |
Production of miRNAs involved in gene silencing by miRNA GO:0035196
Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein.
|
1 | O75569 (/IDA) |
Production of miRNAs involved in gene silencing by miRNA GO:0035196
Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein.
|
1 | Q9WTX2 (/ISO) |
Outer ear morphogenesis GO:0042473
The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull.
|
1 | Q9WTX2 (/IMP) |
Outer ear morphogenesis GO:0042473
The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull.
|
1 | Q2HJ92 (/ISS) |
Middle ear morphogenesis GO:0042474
The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window).
|
1 | Q9WTX2 (/IMP) |
Middle ear morphogenesis GO:0042474
The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window).
|
1 | Q2HJ92 (/ISS) |
Skeletal system morphogenesis GO:0048705
The process in which the anatomical structures of the skeleton are generated and organized.
|
1 | Q9WTX2 (/IMP) |
Skeletal system morphogenesis GO:0048705
The process in which the anatomical structures of the skeleton are generated and organized.
|
1 | Q2HJ92 (/ISS) |
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
1 | O75569 (/IMP) |
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
1 | Q9WTX2 (/ISO) |
Positive regulation of intrinsic apoptotic signaling pathway GO:2001244
Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.
|
1 | Q9WTX2 (/IDA) |
There are 14 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | Q2HJ92 (/ISS) Q4V8C7 (/ISS) Q9WTX2 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | O75569 (/IDA) Q4V8C7 (/IDA) |
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
1 | Q9WTX2 (/IDA) |
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
1 | Q2HJ92 (/ISS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | O75569 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9WTX2 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9WTX2 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O75569 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9WTX2 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O75569 (/TAS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | O75569 (/IDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9WTX2 (/ISO) |
RISC-loading complex GO:0070578
A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from Dicer and TRBP. This complex has endoribonuclease activity.
|
1 | O75569 (/IDA) |
RISC-loading complex GO:0070578
A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from Dicer and TRBP. This complex has endoribonuclease activity.
|
1 | Q9WTX2 (/ISO) |