The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
ATP-grasp fold, A domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22780: Trifunctional purine biosynthetic protein adenosin...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphoribosylamine--glycine ligase. [EC: 6.3.4.13]
ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N(1)- (5-phospho-D-ribosyl)glycinamide.
  • Formerly EC 6.3.1.3.
196 A0A011WMY3 A0A026X2D7 A0A034VBM4 A0A087R938 A0A087X9P8 A0A091GI02 A0A091GWH6 A0A091LGJ0 A0A091MY61 A0A091QE75
(186 more...)
Phosphoribosylformylglycinamidine cyclo-ligase. [EC: 6.3.3.1]
ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.
    138 A0A026X2D7 A0A034VBM4 A0A087R938 A0A087X9P8 A0A091GI02 A0A091GWH6 A0A091LGJ0 A0A091MY61 A0A091QE75 A0A091QHG0
    (128 more...)
    Phosphoribosylglycinamide formyltransferase. [EC: 2.1.2.2]
    10-formyltetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide.
      131 A0A026X2D7 A0A034VBM4 A0A087R938 A0A087X9P8 A0A091GI02 A0A091GWH6 A0A091LGJ0 A0A091MY61 A0A091QE75 A0A091QHG0
      (121 more...)
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