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CATH Superfamily 3.30.1490.20

ATP-grasp fold, A domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
ATP-grasp fold, A domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22634: Phosphoribosylaminoimidazole carboxylase ATPase su...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
5-(carboxyamino)imidazole ribonucleotide synthase. [EC: 6.3.4.18]
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole + HCO(3)(-) = ADP + phosphate + 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole.
  • In Escherichia coli, this enzyme, along with EC 5.4.99.18, is required to carry out the single reaction catalyzed by EC 4.1.1.21 in vertebrates.
  • Carboxyphosphate is the putative acyl phosphate intermediate.
  • Involved in the late stages of purine biosynthesis.
 172 A0A034TN78 A0A034TZC2 A0A061PR06 A0A061QBE2 A0A066UUG7 A0A081NDT9 A0A084TGE7 A0A085PDD4 A0A085T4I0 A0A085TG17
(162 more...)