The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"R3H-like domain
".
FunFam 1514: Poly(A)-specific ribonuclease PARN
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 15 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
4 | P69341 (/ISS) Q5RC51 (/ISS) Q8VDG3 (/ISS) Q90ZA1 (/ISS) |
|
Cation binding GO:0043169
Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge.
|
4 | P69341 (/ISS) Q5RC51 (/ISS) Q8VDG3 (/ISS) Q90ZA1 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O95453 (/IPI) Q8VDG3 (/IPI) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | O95453 (/IDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q8VDG3 (/ISO) |
|
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
|
1 | O95453 (/TAS) |
|
Nuclease activity GO:0004518
Catalysis of the hydrolysis of ester linkages within nucleic acids.
|
1 | O95453 (/TAS) |
|
Poly(A)-specific ribonuclease activity GO:0004535
Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
|
1 | O95453 (/IMP) |
|
Poly(A)-specific ribonuclease activity GO:0004535
Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
|
1 | Q8VDG3 (/ISO) |
|
Poly(A)-specific ribonuclease activity GO:0004535
Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
|
1 | O95453 (/TAS) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | O95453 (/IPI) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q8VDG3 (/ISO) |
|
Cation binding GO:0043169
Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge.
|
1 | O95453 (/IMP) |
|
Cation binding GO:0043169
Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge.
|
1 | Q8VDG3 (/ISO) |
|
Telomerase RNA binding GO:0070034
Interacting selectively and non-covalently with the telomerase RNA template.
|
1 | O95453 (/IC) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
|
1 | Q8VDG3 (/IDA) |
|
Nuclear-transcribed mRNA poly(A) tail shortening GO:0000289
Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
|
1 | O95453 (/TAS) |
|
Female gamete generation GO:0007292
Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction.
|
1 | O95453 (/TAS) |
|
RNA modification GO:0009451
The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
|
1 | O95453 (/TAS) |
|
Positive regulation of telomere maintenance via telomerase GO:0032212
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
|
1 | O95453 (/IMP) |
|
Positive regulation of telomere maintenance via telomerase GO:0032212
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
|
1 | Q8VDG3 (/ISO) |
|
Regulation of mRNA stability GO:0043488
Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
|
1 | O95453 (/TAS) |
|
Positive regulation of telomerase activity GO:0051973
Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
|
1 | O95453 (/IMP) |
|
Positive regulation of telomerase activity GO:0051973
Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
|
1 | Q8VDG3 (/ISO) |
|
RNA phosphodiester bond hydrolysis, exonucleolytic GO:0090503
The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.
|
1 | O95453 (/IMP) |
|
RNA phosphodiester bond hydrolysis, exonucleolytic GO:0090503
The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.
|
1 | Q8VDG3 (/ISO) |
|
Telomerase RNA stabilization GO:0090669
Prevention of degradation of telomerase RNA (TERC) molecules.
|
1 | O95453 (/IMP) |
|
Telomerase RNA stabilization GO:0090669
Prevention of degradation of telomerase RNA (TERC) molecules.
|
1 | Q8VDG3 (/ISO) |
|
Regulation of telomerase RNA localization to Cajal body GO:1904872
Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body.
|
1 | O95453 (/IMP) |
|
Regulation of telomerase RNA localization to Cajal body GO:1904872
Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body.
|
1 | Q8VDG3 (/ISO) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O95453 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | O95453 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O95453 (/TAS) |