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CATH Superfamily 3.30.1300.10

Pantoate-beta-alanine ligase, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2022: Pantothenate synthetase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Pantoate--beta-alanine ligase (AMP-forming). [EC: 6.3.2.1]
ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.
    		 1814 A0A010PN02 A0A011UT41 A0A014L3I4 A0A023BY01 A0A023NN89 A0A023X919 A0A023Y525 A0A024FFY4 A0A024LRX5 A0A024YRW0
    (1804 more...)
    UMP/CMP kinase. [EC: 2.7.4.14]
    (1) ATP + (d)CMP = ADP + (d)CDP. (2) ATP + UMP = ADP + UDP.
    • This eukaryotic enzyme is a bifunctional enzyme that catalyzes the phosphorylation of both CMP and UMP with similar efficiency.
    • dCMP can also act as acceptor.
    • Different from the monofunctional prokaryotic enzymes EC 2.7.4.25, CMP kinase and EC 2.7.4.22, UMP kinase.
    • This eukaryotic enzyme is a bifunctional enzyme that catalyzes the phosphorylation of both CMP and UMP with similar efficiency.
    • dCMP can also act as acceptor.
    • Different from the monofunctional prokaryotic enzymes EC 2.7.4.25 and EC 2.7.4.22.
    • Formerly EC 2.7.4.5.
    		 69 A0A076GYF3 A0A076HAY0 A0A076HCU4 A0A081GLB7 A0A089PJ51 A0A089QMZ1 A0A0A1Z7S7 A0A0A1ZVM1 A0A0A2A359 A0A0A2A9E3
    (59 more...)
    3-methyl-2-oxobutanoate hydroxymethyltransferase. [EC: 2.1.2.11]
    5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H(2)O = tetrahydrofolate + 2-dehydropantoate.
      		 1 B9GBB4
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