The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol (PI) phosphodiesterase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7585: Glycerophosphoryl diester phosphodiesterase 2-like

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycerophosphodiester phosphodiesterase activity GO:0008889
Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.
5 F4HQ30 (/IDA) F4HQ30 (/IDA) P10908 (/IDA) Q7Y208 (/IDA) Q7Y208 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
2 Q7Y208 (/IDA) Q7Y208 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q3KTM2 (/IPI) Q8WTR4 (/IPI)
Glycerophosphodiester phosphodiesterase activity GO:0008889
Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.
2 Q487V1 (/ISS) Q9KRT2 (/ISS)
Glycerophosphocholine phosphodiesterase activity GO:0047389
Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline.
2 P10908 (/IDA) Q640M6 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 P10908 (/IDA)
Glycerophosphodiester phosphodiesterase activity GO:0008889
Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.
1 Q3KTM2 (/IMP)
Glycerophosphodiester phosphodiesterase activity GO:0008889
Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.
1 Q640M6 (/ISO)
Glycerophosphocholine phosphodiesterase activity GO:0047389
Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline.
1 Q640M6 (/EXP)
Glycerophosphoinositol glycerophosphodiesterase activity GO:0047395
Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H(2)O = sn-glycerol 3-phosphate + myo-inositol + H(+).
1 P10908 (/IDA)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Trichome differentiation GO:0010026
The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana.
4 Q9FJ62 (/IGI) Q9FJ62 (/IGI) Q9SZ11 (/IGI) Q9SZ11 (/IGI)
Guard cell morphogenesis GO:0010442
Generation and organization of the polarized cell that is capable of turgor driven movement.
4 Q9FJ62 (/IGI) Q9FJ62 (/IGI) Q9SZ11 (/IGI) Q9SZ11 (/IGI)
Plant-type cell wall cellulose metabolic process GO:0052541
The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall.
4 Q9FJ62 (/IGI) Q9FJ62 (/IGI) Q9SZ11 (/IGI) Q9SZ11 (/IGI)
Phospholipid catabolic process GO:0009395
The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
3 Q487V1 (/ISS) Q83DQ4 (/ISS) Q9KRT2 (/ISS)
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
2 D7SFH9 (/IMP) D7SFH9 (/IMP)
Cellular defense response GO:0006968
A defense response that is mediated by cells.
2 D7SFH9 (/IDA) D7SFH9 (/IDA)
Cell tip growth GO:0009932
Growth that occurs specifically at the tip of a cell.
2 Q9SZ11 (/IMP) Q9SZ11 (/IMP)
Root epidermal cell differentiation GO:0010053
The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast.
2 Q9SZ11 (/IMP) Q9SZ11 (/IMP)
Cellular phosphate ion homeostasis GO:0030643
Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell.
2 F4HQ30 (/IMP) F4HQ30 (/IMP)
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
2 Q3KTM2 (/IMP) Q640M6 (/IMP)
Root hair cell differentiation GO:0048765
The process in which a relatively unspecialized cell acquires specialized features of a root hair cell.
2 Q9SZ11 (/IMP) Q9SZ11 (/IMP)
Generation of precursor metabolites and energy GO:0006091
The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
1 Q83DQ4 (/ISS)
Spinal cord motor neuron differentiation GO:0021522
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
1 Q640M6 (/IMP)
Cerebral cortex neuron differentiation GO:0021895
The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.
1 Q640M6 (/IMP)
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 Q640M6 (/IMP)
Positive regulation of osteoblast differentiation GO:0045669
Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
1 Q9ESM6 (/IDA)
Positive regulation of osteoblast differentiation GO:0045669
Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
1 Q9ESM6 (/IMP)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
1 Q640M6 (/IDA)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
1 Q640M6 (/IMP)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
1 Q640M6 (/ISO)
Positive regulation of cell cycle GO:0045787
Any process that activates or increases the rate or extent of progression through the cell cycle.
1 Q640M6 (/IMP)
Glycerophospholipid catabolic process GO:0046475
The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
1 Q640M6 (/TAS)
Regulation of timing of cell differentiation GO:0048505
The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development.
1 Q640M6 (/IMP)
Actin filament reorganization GO:0090527
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of actin filaments.
1 Q9ESM6 (/IDA)

There are 15 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Anchored component of membrane GO:0031225
The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
12 F4HQ30 (/TAS) F4HQ30 (/TAS) F4JEQ1 (/TAS) F4JEQ1 (/TAS) Q9FGT9 (/TAS) Q9FGT9 (/TAS) Q9FJ62 (/TAS) Q9FJ62 (/TAS) Q9LVN0 (/TAS) Q9LVN0 (/TAS)
(2 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
9 F4HQ30 (/IDA) F4HQ30 (/IDA) Q7Y208 (/IDA) Q7Y208 (/IDA) Q9ESM6 (/IDA) Q9FJ62 (/IDA) Q9FJ62 (/IDA) Q9SZ11 (/IDA) Q9SZ11 (/IDA)
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
6 F4HQ30 (/IDA) F4HQ30 (/IDA) Q9FJ62 (/IDA) Q9FJ62 (/IDA) Q9SZ11 (/IDA) Q9SZ11 (/IDA)
Apoplast GO:0048046
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
6 F4HQ30 (/IDA) F4HQ30 (/IDA) Q9FGT9 (/IDA) Q9FGT9 (/IDA) Q9LVN0 (/IDA) Q9LVN0 (/IDA)
Plant-type cell wall GO:0009505
A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances.
2 Q9SZ11 (/IDA) Q9SZ11 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
2 Q9FJ62 (/IDA) Q9FJ62 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 F4HQ30 (/IDA) F4HQ30 (/IDA)
Anchored component of membrane GO:0031225
The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
2 Q7Y208 (/IDA) Q7Y208 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q640M6 (/TAS)
Actin filament GO:0005884
A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
1 Q9ESM6 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q640M6 (/IDA)
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
1 Q9ESM6 (/IDA)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 Q640M6 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q640M6 (/IDA)
Perinuclear endoplasmic reticulum GO:0097038
The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes.
1 Q640M6 (/IDA)