The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Metal-dependent hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 40287: Putative D-hydantoinase (Dihydropyrimidinase)

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Dihydropyrimidinase. [EC: 3.5.2.2]
5,6-dihydrouracil + H(2)O = 3-ureidopropanoate.
  • Also acts on dihydrothymine and hydantoin.
1996 A0A010YZ03 A0A010YZ03 A0A017H997 A0A017H997 A0A017HAE8 A0A017HAE8 A0A017HF07 A0A017HF07 A0A021X6U8 A0A021X6U8
(1986 more...)
Dihydroorotase. [EC: 3.5.2.3]
(S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate.
    18 B0P512 B0P512 D4JWU1 D4JWU1 D4L9N1 D4L9N1 D4MNS0 D4MNS0 D4MUM2 D4MUM2
    (8 more...)
    Saccharolysin. [EC: 3.4.24.37]
    Cleavage of Pro-|-Phe and Ala-|-Ala bonds.
    • Belongs to peptidase family M3.
    • Formerly EC 3.4.22.22.
    18 A0A0E1X0C6 A0A0E1X0C6 A0A1B3RWV1 A0A1B3RWV1 C0G440 C0G440 C0RGZ7 C0RGZ7 C4WI16 C4WI16
    (8 more...)
    Urease. [EC: 3.5.1.5]
    Urea + H(2)O = CO(2) + 2 NH(3).
      4 A0A1C9VLF5 A0A1C9VLF5 A0A1L1PRN8 A0A1L1PRN8
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