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CATH Superfamily 3.20.20.140

Metal-dependent hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Metal-dependent hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 40244: Probable n-acyl-d-glutamate deacylase protein

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
N-acyl-D-amino-acid deacylase. [EC: 3.5.1.81]
N-acyl-D-amino acid + H(2)O = a carboxylate + D-amino acid.
  • Has a wide specificity; hydrolyzes N-acyl derivative of neutral D-amino acids.
  • Used in separating D- and L-amino acids.
 272 A0A024KLT3 A0A024KLT3 A0A031J305 A0A031J305 A0A058YC58 A0A058YC58 A0A060VA71 A0A060VA71 A0A063BF25 A0A063BF25
(262 more...)
N-acyl-D-aspartate deacylase. [EC: 3.5.1.83]
N-acyl-D-aspartate + H(2)O = a carboxylate + D-aspartate.
    		 64 A0A095Q9W1 A0A095Q9W1 A0A0D6HJ42 A0A0D6HJ42 A0A0E1SEU0 A0A0E1SEU0 A0A0E1U2E7 A0A0E1U2E7 A0A0E1W812 A0A0E1W812
    (54 more...)
    N-acyl-D-glutamate deacylase. [EC: 3.5.1.82]
    N-acyl-D-glutamate + H(2)O = a carboxylate + D-glutamate.
      		 20 A0A0F6ZXV3 A0A0F6ZXV3 A0A157SJJ3 A0A157SJJ3 A9I5U2 A9I5U2 A9IGF2 A9IGF2 D4E4C4 D4E4C4
      (10 more...)
      N-acyl-aliphatic-L-amino acid amidohydrolase. [EC: 3.5.1.14]
      (1) An N-acyl-aliphatic-L-amino acid + H(2)O = an aliphatic L-amino acid + a carboxylate. (2) An N-acetyl-L-cysteine-S-conjugate + H(2)O = an L-cysteine-S- conjugate + acetate.
      • The enzyme is found in animals and is involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate).
      • It acts on mercapturic acids (S-conjugates of N-acetyl-L-cysteine) and neutral aliphatic N-acyl-alpha-amino acids.
      • Some bacterial aminoacylases demonstrate substrate specificity of both EC 3.5.1.14 and EC 3.5.1.114.
      • Cf. EC 3.5.1.15 and EC 3.5.1.114.
      		 4 A0A1B4X4T7 A0A1B4X4T7 Q0K1X5 Q0K1X5
      2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase. [EC: 1.3.1.28]
      2,3-dihydro-2,3-dihydroxybenzoate + NAD(+) = 2,3-dihydroxybenzoate + NADH.
      • Formerly EC 1.1.1.109.
      		 2 G8Q676 G8Q676
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