The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"MutM-like, N-terminal
".
FunFam 500: Probable formamidopyrimidine-DNA glycosylase
There are 2 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
EC Term | Annotations | Evidence |
---|---|---|
DNA-formamidopyrimidine glycosylase.
[EC: 3.2.2.23]
Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.
|
6 | A0A0U2UK72 A0A165XF32 A0A1E1EVZ6 E3VZU5 Q5UQ00 W6GVR4 |
DNA-(apurinic or apyrimidinic site) lyase.
[EC: 4.2.99.18]
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
|
6 | A0A0U2UK72 A0A165XF32 A0A1E1EVZ6 E3VZU5 Q5UQ00 W6GVR4 |