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CATH Superfamily 3.20.19.10

Aconitase, domain 4

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aconitase, domain 4
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1150: Aconitase C-terminal domain protein

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aconitate hydratase. [EC: 4.2.1.3]
Citrate = isocitrate.
  • Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate.
  • The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate.
  • Cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate.
  • Formerly EC 4.2.1.4.
 85 A0A026RRY2 A0A026V2M6 A0A027TYV7 A0A028DM03 A0A066Q2W7 A0A069XPB0 A0A070DD29 A0A073G0Y5 A0A073GIS2 A0A074ISB7
(75 more...)
Dimethylmaleate hydratase. [EC: 4.2.1.85]
(2R,3S)-2,3-dimethylmalate = dimethylmaleate + H(2)O.
  • Inhibited by oxygen.
  • Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri.
  • Other enzymes involved in this pathway are EC 1.17.5.1, EC 1.3.7.1, EC 3.5.2.18, EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6 and EC 4.1.3.32.
 44 A0A024KR45 A0A029KZ69 A0A037Y9C7 A0A069XPB0 A0A0E0TVL6 A0A0E1LWP8 A0A0H0QA65 A0A0H3X5U8 A0A0I0MQI9 A0A0K3QNZ4
(34 more...)