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CATH Superfamily 3.10.450.50

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 23232: Bile acid 7-alpha dehydratase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Scytalone dehydratase. [EC: 4.2.1.94]
Scytalone = 1,3,8-trihydroxynaphthalene + H(2)O.
  • Involved with EC 1.1.1.252 in the biosynthesis of melanin in pathogenic fungi.
 100 A0A010QV22 A0A024B3Z3 A0A066XFN7 A0A074WEF9 A0A074WSD5 A0A074YDS2 A0A0B0DX22 A0A0D2A951 A0A0D2ACP8 A0A0D2BF25
(90 more...)
Bile-acid 7-alpha-dehydratase. [EC: 4.2.1.106]
7-alpha,12-alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA = 12-alpha-hydroxy- 3-oxochola-4,6-dien-24-oyl-CoA + H(2)O.
  • This enzyme, characterized from the gut bacterium Clostridium scindens (previously known as Eubacterium sp. strain VPI 12708), participates in the 7-dehydroxylation process associated with bile acid degradation.
 4 B0NI18 B4YSU1 P19412 Q9RB47
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