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CATH Superfamily 3.10.450.50

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 23035: Benzoate 1,2-dioxygenase subunit beta

There are 6 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Benzoate 1,2-dioxygenase. [EC: 1.14.12.10]
Benzoate + NADH + O(2) = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1- carboxylate + NAD(+).
  • A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), and an iron-sulfur oxygenase.
  • Formerly EC 1.13.99.2.
 410 A0A009FU37 A0A009FU37 A0A009GCD0 A0A009GCD0 A0A009H104 A0A009H104 A0A009H8Q3 A0A009H8Q3 A0A009HMR8 A0A009HMR8
(400 more...)
2-halobenzoate 1,2-dioxygenase. [EC: 1.14.12.13]
A 2-halobenzoate + NADH + O(2) = catechol + a halide anion + NAD(+) + CO(2).
  • A multicomponent enzyme system composed of a dioxygenase component and an electron transfer component.
  • The latter contains FAD.
  • The enzyme, characterized from the bacterium Burkholderia cepacia 2CBS, has a broad substrate specificity.
  • Substrates include 2-fluorobenzoate, 2-chlorobenzoate, 2-bromobenzoate, and 2-iodobenzoate, which are processed in this order of preference.
 150 A0A009H104 A0A009H104 A0A009HMR8 A0A009HMR8 A0A009K125 A0A009K125 A0A009SVA1 A0A009SVA1 A0A062FN72 A0A062FN72
(140 more...)
Anthranilate 1,2-dioxygenase (deaminating, decarboxylating). [EC: 1.14.12.1]
Anthranilate + NAD(P)H + O(2) = catechol + CO(2) + NAD(P)(+) + NH(3).
    		 50 A0A024HG65 A0A024HG65 A0A069QAK3 A0A069QAK3 A0A081YFJ7 A0A081YFJ7 A0A0C6EGS7 A0A0C6EGS7 A0A0E1AXS1 A0A0E1AXS1
    (40 more...)
    Toluene dioxygenase. [EC: 1.14.12.11]
    Toluene + NADH + O(2) = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+).
    • A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), an iron-sulfur oxygenase, and a ferredoxin.
    • Some other aromatic compounds, including ethylbenzene, 4-xylene and some halogenated toluenes, are converted into the corresponding cis- dihydrodiols.
    		 18 A0A1H0T5J7 A0A1H0T5J7 A0A1J0F0V2 A0A1J0F0V2 A0A1K2BXK3 A0A1K2BXK3 A0A1K2CAI7 A0A1K2CAI7 A0A1K2EAD2 A0A1K2EAD2
    (8 more...)
    Chloromuconate cycloisomerase. [EC: 5.5.1.7]
    (2R)-2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis- muconate.
    • Spontaneous elimination of HCl produces cis-4-carboxymethylenebut-2- en-4-olide.
    • Also acts in reverse direction on 2-chloro-cis,cis-muconate.
    • Not identical with EC 5.5.1.1 or EC 5.5.1.11.
    		 2 G8Q211 G8Q211
    Muconate cycloisomerase. [EC: 5.5.1.1]
    (+)-muconolactone = cis,cis-muconate.
    • Also acts, in the reverse reaction, on 3-methyl-cis,cis-muconate and, very slowly, on cis,trans-muconate.
    • Not identical with EC 5.5.1.7 or EC 5.5.1.11.
    		 2 G8Q211 G8Q211