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CATH Superfamily 3.10.450.40

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4052: Peroxisomal primary amine oxidase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Primary-amine oxidase. [EC: 1.4.3.21]
RCH(2)NH(2) + H(2)O + O(2) = RCHO + NH(3) + H(2)O(2).
  • A group of enzymes that oxidize primary monoamines but have little or no activity toward diamines, such as histamine, or toward secondary and tertiary amines.
  • They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone) and, unlike EC 1.4.3.4, are sensitive to inhibition by carbonyl-group reagents, such as semicarbazide.
  • In some mammalian tissues the enzyme also functions as a vascular- adhesion protein (VAP-1).
  • Formerly EC 1.4.3.6.
 28 A0A070UZ51 A0A074J581 A0A0E1M1G5 A0A0E2TNQ9 A0A125X4W4 A0A142UWS1 A0A1J0HAY5 D8AMG6 D8AY83 E1HRF1
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