The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Microbial ribonucleases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 603: Guanyl-specific ribonuclease f1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Ribonuclease T(1). [EC: 3.1.27.3]
Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in G-P with 2',3'-cyclic phosphate intermediates.
  • Formerly EC 2.7.7.26 and EC 3.1.4.8.
21 A0A0J5PRC2 A0A0P4UNG2 A0A1L7VC99 A7M7A2 B0YEP3 B8NCN3 D4AVI0 I8IAP8 P00651 P00652
(11 more...)
Ribonuclease U(2). [EC: 3.1.27.4]
Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in A-P or G-P with 2',3'-cyclic phosphate intermediates.
    1 P00654
    RRNA endonuclease. [EC: 3.1.27.10]
    Hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes.
    • Also acts on bacterial rRNA.
    1 P00655
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